Detailed information of TA system TA215529

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 436897..437464
• Replicon: chromosome
• Accession: NZ_CP082909
• Organism: Endozoicomonas sp. 4G

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: K7B67_RS02105
• Protein ID: WP_252178719.1
• Coordinates: 436897..437181 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: K7B67_RS02110
• Protein ID: WP_252178720.1
• Coordinates: 437174..437464 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K7B67_RS02095	432456..434159	-	1704	WP_252178717.1	F-box/WD repeat-containing protein	-
K7B67_RS02100	434177..436786	-	2610	WP_252178718.1	ATP-binding cassette domain-containing protein	-
K7B67_RS02105	436897..437181	-	285	WP_252178719.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
K7B67_RS02110	437174..437464	-	291	WP_252178720.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
K7B67_RS02115	437530..438504	-	975	WP_252178721.1	DUF523 and DUF1722 domain-containing protein	-
K7B67_RS02120	438567..439985	-	1419	WP_252178722.1	deoxyribodipyrimidine photo-lyase	-
K7B67_RS02125	440191..440730	+	540	WP_256484679.1	chorismate mutase	-
K7B67_RS02130	440844..441926	+	1083	WP_252178724.1	C2H2-type zinc finger protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-68)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10715.49 Da
• Isoelectric Point: 9.8805

>T215529 WP_252178719.1 NZ_CP082909:c437181-436897 [Endozoicomonas sp. 4G]
VHKLEWLSLARNDLLAIVDYISDDNPKAALRLKDDIQAKAEKLMDFPKIGKVGRIEGTRELVAFGNYIIVYRESGTIIRI
LRILHAAQQWPSSK

Nucleotide

• Length: 285 bp

>T215529 NZ_CP110810:c10744-10460 [Pseudomonas syringae]
ATGAAAGAACAAATTTTCGATTACGACCCAGCAGCAGCCCTTGACGGGCCTGAGGCAATCGCTATTTTTATCTCTGACGC
ATTTGAGACGGGGGATGCGGAGTACATCGCGAAGGCTATGGGGGTTGTCGCAAGGGCCAAAGGGATGAGCGAGCTTGCGC
GTGAGACAGGTCTTTCTCGAGAGCAGCTTTACAGATCGTTCAGTAGCAAGGGCAATCCAACCTTAAAAACCATGTTGACG
GTAATGAGAGCCCTGGGCGTGGACATGACAGCTCGAATGCACTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10832.42 Da
• Isoelectric Point: 6.8822

>AT215529 WP_252178720.1 NZ_CP082909:c437464-437174 [Endozoicomonas sp. 4G]
MAHTSMLHVRVDDTLKKEATEKLANFGLTLSDAVRILLTRITKEGGLPVGLTSDPEAHDAWFRERVKEALNSEEVLPHSQ
VMDDVQALIERKKRRA

Nucleotide

• Length: 291 bp

>AT215529 NZ_CP110810:c11040-10741 [Pseudomonas syringae]
ATGACGACGATAAAACAGACATCTACCTATATGGCTTGGGAACGCAGGCTCAAAGACCAAAAGGCCAAAGCTGCAATTGC
CGCTCGTATTTTTAGAGTTGCAAATGGCCTGATGGGTGATGTCTCGCCAGTAGGGCAGGGCGTGAGTGAGCTACGGATAC
ACGTTGGCCCTGGTTACCGTGTTTATTTCCAGCAGCGAGGCGATGAACTGATCTTGCTGCTGTGCGGTGGTGACAAGAGC
AGCCAATCCCGAGATATCGAAACAGCAAAGAGACTGGCTGATCAATGGAGGCAAGAATGA