Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 324038..324629 Replicon chromosome
Accession NZ_CP082909
Organism Endozoicomonas sp. 4G

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag K7B67_RS01670 Protein ID WP_252178634.1
Coordinates 324038..324346 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag K7B67_RS01675 Protein ID WP_252178635.1
Coordinates 324336..324629 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7B67_RS01645 319338..320072 + 735 WP_252178629.1 FliA/WhiG family RNA polymerase sigma factor -
K7B67_RS01650 320077..320928 + 852 WP_252178630.1 flagellar motor stator protein MotA -
K7B67_RS01655 320928..321896 + 969 WP_252178631.1 flagellar motor protein MotB -
K7B67_RS01660 321893..322699 - 807 WP_252178632.1 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA -
K7B67_RS01665 322809..323780 + 972 WP_252178633.1 glucokinase -
K7B67_RS01670 324038..324346 + 309 WP_252178634.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K7B67_RS01675 324336..324629 + 294 WP_252178635.1 putative addiction module antidote protein Antitoxin
K7B67_RS01680 324706..326130 - 1425 WP_252178636.1 maltoporin LamB -
K7B67_RS01685 326455..327612 + 1158 WP_252178637.1 MalM family protein -
K7B67_RS01690 327698..327955 + 258 WP_252178638.1 type II toxin-antitoxin system Phd/YefM family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-89)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11686.65 Da        Isoelectric Point: 10.8371

>T215528 WP_252178634.1 NZ_CP082909:324038-324346 [Endozoicomonas sp. 4G]
MITVKQHDVFRKWLKALKDQKAKSSILSRVKRLEFGLFGDVKPVGGGLSELRVDTGKGYRVYFVRQGSELIIVFCGSQKK
DQQKQIDLAKALYKDWRANNGR

Download         Length: 309 bp

>T215528 NZ_CP110809:4354723-4355004 [Pseudomonas syringae]
ATGCTGGTTGAGTGGCGGCCGGCAGCACGAATGAACCTGAAGCAAATACTTTCCTACATCGCAGACAGAAATATACGAGC
AGCCAGCGAACTGGGAATGGCAATAGAAGTAGCCACTTCAGCCCTACCTCAACATCCTTACTTGTATCGCCATGGGCGAG
TGCATGGAACAAGGGAAATCGTTGTCCACCCTAATTATCTCGTTGTTTACAAAGTGACAGATCGGATCGAAGTTCTCGCT
GTACTTCACGCCAGGCAAGCCTACCCTACCGACGCTGGGTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10365.79 Da        Isoelectric Point: 4.7914

>AT215528 WP_252178635.1 NZ_CP082909:324336-324629 [Endozoicomonas sp. 4G]
MDGKITDFDPAEFLDSDEAIQHYIDEAVATGHAGFIADSLGVIARARGMSKLAKETGLSRESLYRSLSEEGNPNLKTLLA
VCKALGVSMNIGKPLQV

Download         Length: 294 bp

>AT215528 NZ_CP110809:4354542-4354733 [Pseudomonas syringae]
ATGAGCGCTCGAATTTCTCCAATCGTGTCGGAGTTTGAAACCGAGGAACAGGCCGCCAGCTACGACAAGTGGTTTCGTGC
GCAGGTCCAGGCGTCAATCAATGATCCGGCACCCAATATTTCACACGATCAGGTCATGGCCGAGATGCGTGCGCTTCTAG
AGTCTAAGCAGCCCCCGTCAGATGCTGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References