Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 844045..844702 | Replicon | chromosome |
Accession | NZ_CP082898 | ||
Organism | Klebsiella aerogenes strain KAE3SP |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A0H3FM52 |
Locus tag | K6006_RS04115 | Protein ID | WP_015369792.1 |
Coordinates | 844292..844702 (+) | Length | 137 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | - |
Locus tag | K6006_RS04110 | Protein ID | WP_032709107.1 |
Coordinates | 844045..844311 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
K6006_RS04085 (K6006_04080) | 839272..840705 | - | 1434 | WP_032712496.1 | 6-phospho-beta-glucosidase BglA | - |
K6006_RS04090 (K6006_04085) | 840825..841553 | - | 729 | WP_015369788.1 | MurR/RpiR family transcriptional regulator | - |
K6006_RS04095 (K6006_04090) | 841604..841915 | + | 312 | WP_015703422.1 | N(4)-acetylcytidine aminohydrolase | - |
K6006_RS04100 (K6006_04095) | 842080..842739 | + | 660 | WP_008806429.1 | hemolysin III family protein | - |
K6006_RS04105 (K6006_04100) | 842838..843821 | - | 984 | WP_032709108.1 | tRNA-modifying protein YgfZ | - |
K6006_RS04110 (K6006_04105) | 844045..844311 | + | 267 | WP_032709107.1 | FAD assembly factor SdhE | Antitoxin |
K6006_RS04115 (K6006_04110) | 844292..844702 | + | 411 | WP_015369792.1 | protein YgfX | Toxin |
K6006_RS04120 (K6006_04115) | 844710..845231 | - | 522 | WP_015369793.1 | flavodoxin FldB | - |
K6006_RS04125 (K6006_04120) | 845332..846228 | + | 897 | WP_015703420.1 | site-specific tyrosine recombinase XerD | - |
K6006_RS04130 (K6006_04125) | 846251..846964 | + | 714 | WP_015369795.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
K6006_RS04135 (K6006_04130) | 846970..848703 | + | 1734 | WP_015369796.1 | single-stranded-DNA-specific exonuclease RecJ | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 15887.69 Da Isoelectric Point: 10.0200
>T215504 WP_015369792.1 NZ_CP082898:844292-844702 [Klebsiella aerogenes]
VVLWQSDLRISWRSQWFSLLLHGVVAAIVLLMPWPLSYTPIWLLLLSLVVFDCVRSQRRIHACQGEIKLLIDSRLRWQKT
EWDIVGTPWVISSGMLLRLKHAETGRSQHLWVAADSMDAGEWRDLRRLVLQKPAHD
VVLWQSDLRISWRSQWFSLLLHGVVAAIVLLMPWPLSYTPIWLLLLSLVVFDCVRSQRRIHACQGEIKLLIDSRLRWQKT
EWDIVGTPWVISSGMLLRLKHAETGRSQHLWVAADSMDAGEWRDLRRLVLQKPAHD
Download Length: 411 bp
>T215504 NZ_CP110791:2441003-2441287 [Yersinia sp. SCPM-O-B-9106 (C-191)]
ATGACTTATAATCTTGATTTTGATCGCCGGGCGCTAAAGGAATGGCATAAGCTCGGCGATACCGTACGCCAGCAATTTAA
GAAAAAGCTGCTCGAAGTGATTAAAAATCCACGCGTTGAAGCCAATAAACTGCGCGACTTACCTGATTGTTACAAAATAA
AACTACGCAGCGCCGGATACCGCCTGATTTATCAGGTGCAAGACGAAAAAATCACGGTTTTTGTGGTTGCCGTGGGTAAA
CGGGATCGTGAAGAAGCCTACAGTGAAGCTGGCAATCGCGTCTGA
ATGACTTATAATCTTGATTTTGATCGCCGGGCGCTAAAGGAATGGCATAAGCTCGGCGATACCGTACGCCAGCAATTTAA
GAAAAAGCTGCTCGAAGTGATTAAAAATCCACGCGTTGAAGCCAATAAACTGCGCGACTTACCTGATTGTTACAAAATAA
AACTACGCAGCGCCGGATACCGCCTGATTTATCAGGTGCAAGACGAAAAAATCACGGTTTTTGTGGTTGCCGTGGGTAAA
CGGGATCGTGAAGAAGCCTACAGTGAAGCTGGCAATCGCGTCTGA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10609.12 Da Isoelectric Point: 5.6963
>AT215504 WP_032709107.1 NZ_CP082898:844045-844311 [Klebsiella aerogenes]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDDDKRLFIRLLENDDPDLFNWLMNHGKPADTQLQRMINLIQTRN
RERGPVAI
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDDDKRLFIRLLENDDPDLFNWLMNHGKPADTQLQRMINLIQTRN
RERGPVAI
Download Length: 267 bp
>AT215504 NZ_CP110791:2440774-2441013 [Yersinia sp. SCPM-O-B-9106 (C-191)]
ATGGGTAACATTAATATTCGCATTGATGATGACTTAAAAGATCGTTCTTATGCGGTACTGGAAAAGCTGGGGGTCACCCC
CTCTGATTTGCTGCGCCAGACACTGGAATATGTGGCACAAAGTGGCAAACTGCCCTTTAAATCCGTGTTGCTGACCGATG
AAGATCAAGCACTGGTCGCCGTAGTCAGAGAACGTTTAGCCAATCCACAACCGGTCAGGGTGTCACTGGATGACTTATAA
ATGGGTAACATTAATATTCGCATTGATGATGACTTAAAAGATCGTTCTTATGCGGTACTGGAAAAGCTGGGGGTCACCCC
CTCTGATTTGCTGCGCCAGACACTGGAATATGTGGCACAAAGTGGCAAACTGCCCTTTAAATCCGTGTTGCTGACCGATG
AAGATCAAGCACTGGTCGCCGTAGTCAGAGAACGTTTAGCCAATCCACAACCGGTCAGGGTGTCACTGGATGACTTATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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