Detailed information of TA system TA021543

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): slvAT/RES(toxin)
• Location: 279471..280348
• Replicon: plasmid 2
• Accession: NC_007950
• Organism: Polaromonas sp. JS666

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: -
• Locus tag: BPRO_RS27635
• Protein ID: WP_041390731.1
• Coordinates: 279821..280348 (+)
• Length: 176 a.a.

Antitoxin (Protein)

• Gene name: slvA
• Uniprot ID: -
• Locus tag: BPRO_RS27630
• Protein ID: WP_157046090.1
• Coordinates: 279471..279824 (+)
• Length: 118 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BPRO_RS27615	274489..275562	-	1074	Protein_272	Tn3 family transposase	-
BPRO_RS29220	275577..276132	+	556	Protein_273	recombinase family protein	-
BPRO_RS27625	276145..279167	+	3023	Protein_274	Tn3 family transposase	-
BPRO_RS27630	279471..279824	+	354	WP_157046090.1	DUF2384 domain-containing protein	Antitoxin
BPRO_RS27635	279821..280348	+	528	WP_041390731.1	RES domain-containing protein	Toxin
BPRO_RS27640	280762..280983	-	222	WP_041390733.1	hypothetical protein	-
BPRO_RS27645	281046..282719	-	1674	WP_011486358.1	site-specific integrase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..338007	338007

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (14-167)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 176 a.a.
• Molecular weight: 19128.91 Da
• Isoelectric Point: 4.5183

>T21543 WP_041390731.1 NC_007950:279821-280348 [Polaromonas sp. JS666]
MIAAVSIGLTDQVCYRMHVPRWAWAPTSGLGAARQGGRLNRAGVEALYLALDTETAIAEFQQAAALLPPATLVTYQLTLD
KVVDFRAGFTPDWNPLWQDLSCDWRAMVFDDNVEPPTWVISDMCIAKGYKGILFPSSALAGGNNLVIFNSSIVATDKLEI
FDPKGDLPKNQASWP

Nucleotide

• Length: 528 bp

>T21543 NC_007950:279821-280348 [Polaromonas sp. JS666]
ATGATCGCCGCGGTAAGTATCGGATTGACCGACCAGGTCTGCTACCGAATGCATGTGCCGCGCTGGGCGTGGGCCCCCAC
CAGTGGCCTGGGCGCCGCACGCCAAGGTGGCCGCCTCAACCGTGCTGGCGTCGAGGCGCTTTACTTGGCATTGGACACGG
AGACGGCGATCGCGGAGTTCCAGCAAGCGGCGGCGCTGCTTCCGCCGGCGACGTTGGTAACTTACCAGTTGACCCTGGAC
AAAGTCGTCGACTTCAGGGCGGGCTTCACTCCGGACTGGAATCCGCTGTGGCAGGACTTGTCTTGCGACTGGCGCGCCAT
GGTTTTCGATGACAACGTGGAGCCTCCAACCTGGGTGATTTCGGACATGTGCATCGCCAAGGGCTACAAGGGCATTCTTT
TCCCCTCCAGCGCGCTTGCCGGTGGCAACAACCTCGTGATTTTCAACTCCAGCATCGTTGCGACGGACAAGCTCGAGATA
TTCGATCCAAAGGGCGACTTGCCCAAAAACCAAGCGTCTTGGCCATAA

Antitoxin

Protein

• Length: 118 a.a.
• Molecular weight: 12595.24 Da
• Isoelectric Point: 7.3155

>AT21543 WP_157046090.1 NC_007950:279471-279824 [Polaromonas sp. JS666]
IADALKEPGQDPLISPTRYIDMLKLDIGTFAQHAHVHRNTVTRAPGAASVQSYLRQNIRVLAAALNASGNDLGKALQWFR
NEPLPPFAYKTAEQLVADGRADDVIRLIDSYAGGAAG

Nucleotide

• Length: 354 bp

>AT21543 NC_007950:279471-279824 [Polaromonas sp. JS666]
ATTGCTGATGCACTCAAGGAGCCTGGCCAGGATCCGCTGATTTCTCCCACGCGCTACATAGACATGCTCAAGCTCGACAT
TGGGACATTCGCCCAACACGCGCACGTCCACAGGAACACGGTAACCCGTGCGCCGGGCGCCGCGAGCGTGCAAAGCTACC
TCCGCCAAAACATACGCGTCCTTGCTGCCGCTCTGAATGCATCTGGCAATGACCTCGGGAAGGCCCTGCAGTGGTTTCGT
AATGAACCGCTGCCACCATTCGCCTACAAGACTGCTGAGCAGCTGGTCGCTGACGGCCGCGCGGATGACGTGATCCGCCT
GATTGACTCGTACGCCGGCGGCGCGGCCGGATGA