Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 279471..280348 Replicon plasmid 2
Accession NC_007950
Organism Polaromonas sp. JS666

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag BPRO_RS27635 Protein ID WP_041390731.1
Coordinates 279821..280348 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag BPRO_RS27630 Protein ID WP_157046090.1
Coordinates 279471..279824 (+) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BPRO_RS27615 274489..275562 - 1074 Protein_272 Tn3 family transposase -
BPRO_RS29220 275577..276132 + 556 Protein_273 recombinase family protein -
BPRO_RS27625 276145..279167 + 3023 Protein_274 Tn3 family transposase -
BPRO_RS27630 279471..279824 + 354 WP_157046090.1 DUF2384 domain-containing protein Antitoxin
BPRO_RS27635 279821..280348 + 528 WP_041390731.1 RES domain-containing protein Toxin
BPRO_RS27640 280762..280983 - 222 WP_041390733.1 hypothetical protein -
BPRO_RS27645 281046..282719 - 1674 WP_011486358.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..338007 338007


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(14-167)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19128.91 Da        Isoelectric Point: 4.5183

>T21543 WP_041390731.1 NC_007950:279821-280348 [Polaromonas sp. JS666]
MIAAVSIGLTDQVCYRMHVPRWAWAPTSGLGAARQGGRLNRAGVEALYLALDTETAIAEFQQAAALLPPATLVTYQLTLD
KVVDFRAGFTPDWNPLWQDLSCDWRAMVFDDNVEPPTWVISDMCIAKGYKGILFPSSALAGGNNLVIFNSSIVATDKLEI
FDPKGDLPKNQASWP

Download         Length: 528 bp

>T21543 NC_007950:279821-280348 [Polaromonas sp. JS666]
ATGATCGCCGCGGTAAGTATCGGATTGACCGACCAGGTCTGCTACCGAATGCATGTGCCGCGCTGGGCGTGGGCCCCCAC
CAGTGGCCTGGGCGCCGCACGCCAAGGTGGCCGCCTCAACCGTGCTGGCGTCGAGGCGCTTTACTTGGCATTGGACACGG
AGACGGCGATCGCGGAGTTCCAGCAAGCGGCGGCGCTGCTTCCGCCGGCGACGTTGGTAACTTACCAGTTGACCCTGGAC
AAAGTCGTCGACTTCAGGGCGGGCTTCACTCCGGACTGGAATCCGCTGTGGCAGGACTTGTCTTGCGACTGGCGCGCCAT
GGTTTTCGATGACAACGTGGAGCCTCCAACCTGGGTGATTTCGGACATGTGCATCGCCAAGGGCTACAAGGGCATTCTTT
TCCCCTCCAGCGCGCTTGCCGGTGGCAACAACCTCGTGATTTTCAACTCCAGCATCGTTGCGACGGACAAGCTCGAGATA
TTCGATCCAAAGGGCGACTTGCCCAAAAACCAAGCGTCTTGGCCATAA

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 12595.24 Da        Isoelectric Point: 7.3155

>AT21543 WP_157046090.1 NC_007950:279471-279824 [Polaromonas sp. JS666]
IADALKEPGQDPLISPTRYIDMLKLDIGTFAQHAHVHRNTVTRAPGAASVQSYLRQNIRVLAAALNASGNDLGKALQWFR
NEPLPPFAYKTAEQLVADGRADDVIRLIDSYAGGAAG

Download         Length: 354 bp

>AT21543 NC_007950:279471-279824 [Polaromonas sp. JS666]
ATTGCTGATGCACTCAAGGAGCCTGGCCAGGATCCGCTGATTTCTCCCACGCGCTACATAGACATGCTCAAGCTCGACAT
TGGGACATTCGCCCAACACGCGCACGTCCACAGGAACACGGTAACCCGTGCGCCGGGCGCCGCGAGCGTGCAAAGCTACC
TCCGCCAAAACATACGCGTCCTTGCTGCCGCTCTGAATGCATCTGGCAATGACCTCGGGAAGGCCCTGCAGTGGTTTCGT
AATGAACCGCTGCCACCATTCGCCTACAAGACTGCTGAGCAGCTGGTCGCTGACGGCCGCGCGGATGACGTGATCCGCCT
GATTGACTCGTACGCCGGCGGCGCGGCCGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References