Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2037705..2037850 Replicon chromosome
Accession NZ_CP082840
Organism Klebsiella pneumoniae strain W09308

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2037741..2037843 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2037705..2037850 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6041_RS09985 (K6041_09980) 2032835..2034895 + 2061 WP_004151449.1 oligopeptidase B -
K6041_RS09990 (K6041_09985) 2034899..2035558 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6041_RS09995 (K6041_09990) 2035637..2035867 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6041_RS10000 (K6041_09995) 2035980..2036354 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6041_RS10005 (K6041_10000) 2036358..2037227 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
K6041_RS10010 (K6041_10005) 2037244..2037582 + 339 WP_002911404.1 YebY family protein -
- 2037705..2037850 - 146 - - Antitoxin
- 2037741..2037843 + 103 - - Toxin
K6041_RS10015 (K6041_10010) 2038218..2038361 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6041_RS10020 (K6041_10015) 2038466..2039434 - 969 WP_004151446.1 VirK/YbjX family protein -
K6041_RS10025 (K6041_10020) 2039591..2040244 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K6041_RS10030 (K6041_10025) 2040241..2040432 - 192 WP_002911395.1 YebW family protein -
K6041_RS10035 (K6041_10030) 2040530..2040769 - 240 WP_002911393.1 YebV family protein -
K6041_RS10040 (K6041_10035) 2040885..2042318 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T215406 NZ_CP082840:2037741-2037843 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT215406 NZ_CP082840:c2037850-2037705 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References