Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2447986..2448257 Replicon chromosome
Accession NZ_CP082835
Organism Escherichia coli strain 1613

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2448024..2448127 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2447986..2448257 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8O78_RS12205 2445143..2446582 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
K8O78_RS12210 2446700..2446936 + 237 WP_001295499.1 YebV family protein -
K8O78_RS12215 2447041..2447232 + 192 WP_001296140.1 YebW family protein -
K8O78_RS12220 2447233..2447889 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2447986..2448257 + 272 - - Antitoxin
- 2448024..2448127 - 104 - - Toxin
K8O78_RS12225 2448285..2448626 - 342 WP_000976483.1 YebY family protein -
K8O78_RS12230 2448639..2449511 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
K8O78_RS12235 2449515..2449889 - 375 WP_000168751.1 CopC domain-containing protein YobA -
K8O78_RS12240 2450028..2450258 + 231 WP_000916763.1 DNA polymerase III subunit theta -
K8O78_RS12245 2450360..2451016 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
K8O78_RS12250 2451040..2451702 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T215376 NZ_CP082835:c2448127-2448024 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT215376 NZ_CP082835:2447986-2448257 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References