Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1949756..1950024 Replicon chromosome
Accession NC_007946
Organism Escherichia coli UTI89

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1949794..1949896 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1949756..1950024 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
UTI89_RS09890 1946913..1948352 + 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
UTI89_RS09895 1948470..1948706 + 237 WP_001295499.1 DUF1480 family protein -
UTI89_RS09900 1948811..1949002 + 192 WP_001296140.1 YebW family protein -
UTI89_RS09905 1949003..1949659 - 657 WP_000812741.1 protein-serine/threonine phosphatase -
- 1949756..1950024 + 269 - - Antitoxin
- 1949794..1949896 - 103 - - Toxin
UTI89_RS09915 1950054..1950395 - 342 WP_000984819.1 YebY family protein -
UTI89_RS09920 1950408..1951280 - 873 WP_000879320.1 copper homeostasis membrane protein CopD -
UTI89_RS09925 1951284..1951658 - 375 WP_000168747.1 CopC domain-containing protein YobA -
UTI89_RS09930 1951797..1952027 + 231 WP_000916763.1 DNA polymerase III subunit theta -
UTI89_RS09935 1952129..1952785 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
UTI89_RS09940 1952808..1953470 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T21523 NC_007946:c1949896-1949794 [Escherichia coli UTI89]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT21523 NC_007946:1949756-1950024 [Escherichia coli UTI89]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References