Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1920605..1921135 Replicon chromosome
Accession NZ_CP082807
Organism Burkholderia contaminans strain SCAID TST1-2021 (11/270)

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag K8B66_RS08810 Protein ID WP_232490759.1
Coordinates 1920896..1921135 (+) Length 80 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag K8B66_RS08805 Protein ID WP_076841742.1
Coordinates 1920605..1920850 (+) Length 82 a.a.

Genomic Context

K8B66_RS08775K8B66_RS08780K8B66_RS37960K8B66_RS37965K8B66_RS08800K8B66_RS08805K8B66_RS08810K8B66_RS08790K8B66_RS08795K8B66_RS08815K8B66_RS08820K8B66_RS08825K8B66_RS08830
Location: 1915670..1916686 (1017 bp)
Type: Others
Protein ID: WP_039358635.1
Location: 1916936..1917202 (267 bp)
Type: Others
Protein ID: WP_046196769.1
Location: 1917199..1917360 (162 bp)
Type: Others
Protein ID: WP_223274361.1
Location: 1917388..1917615 (228 bp)
Type: Others
Protein ID: WP_223274360.1
Location: 1919325..1920488 (1164 bp)
Type: Others
Protein ID: WP_039358627.1
Location: 1920605..1920850 (246 bp)
Type: Antitoxin
Protein ID: WP_076841742.1
Location: 1920896..1921135 (240 bp)
Type: Toxin
Protein ID: WP_232490759.1
Location: 1917664..1917903 (240 bp)
Type: Others
Protein ID: Protein_1721
Location: 1917917..1919005 (1089 bp)
Type: Others
Protein ID: WP_249215684.1
Location: 1921206..1922510 (1305 bp)
Type: Others
Protein ID: WP_039358619.1
Location: 1922513..1923115 (603 bp)
Type: Others
Protein ID: WP_039358616.1
Location: 1923153..1923530 (378 bp)
Type: Others
Protein ID: WP_039358613.1
Location: 1923527..1924276 (750 bp)
Type: Others
Protein ID: WP_039358610.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
K8B66_RS08775 (K8B66_08775)1915670..1916686+1017WP_039358635.1GNAT family N-acetyltransferase-
K8B66_RS08780 (K8B66_08780)1916936..1917202+267WP_046196769.1type II toxin-antitoxin system VapB family antitoxin-
K8B66_RS379601917199..1917360+162WP_223274361.1type II toxin-antitoxin system VapC family toxin-
K8B66_RS379651917388..1917615+228WP_223274360.1hypothetical protein-
K8B66_RS08790 (K8B66_08790)1917664..1917903-240Protein_1721nucleotidyltransferase-
K8B66_RS08795 (K8B66_08795)1917917..1919005-1089WP_249215684.1type IV toxin-antitoxin system AbiEi family antitoxin-
K8B66_RS08800 (K8B66_08800)1919325..1920488+1164WP_039358627.1M20 aminoacylase family protein-
K8B66_RS08805 (K8B66_08805)1920605..1920850+246WP_076841742.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
K8B66_RS08810 (K8B66_08810)1920896..1921135+240WP_232490759.1type II toxin-antitoxin system RelE/ParE family toxinToxin
K8B66_RS08815 (K8B66_08815)1921206..1922510-1305WP_039358619.1cobyrinate a,c-diamide synthase-
K8B66_RS08820 (K8B66_08820)1922513..1923115-603WP_039358616.1cob(I)yrinic acid a,c-diamide adenosyltransferase-
K8B66_RS08825 (K8B66_08825)1923153..1923530-378WP_039358613.1cobalamin biosynthesis protein-
K8B66_RS08830 (K8B66_08830)1923527..1924276-750WP_039358610.1uroporphyrinogen-III C-methyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(1-74)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 80 a.a.        Molecular weight: 9325.66 Da        Isoelectric Point: 8.0671

>T215162 WP_232490759.1 NZ_CP082807:1920896-1921135 [Burkholderia contaminans]
IWRDTVGRGSLKQTDLYHRDLIGTMEALARGEKVGRTCIVRDGYFRYAVGSHVVFYRETEYTIDLIRVLHQRMDIEQHL

Download         Length: 240 bp

>T215162 NZ_CP110515:235062-235346 [Klebsiella pneumoniae]
ATGACTTATAAGCTGGCCTTTAATGAATCAGCTCTGAAAGAATGGAAAAAATTGGGCCATACCATTCGGGAACAATTCAA
AAAGAAGCTCGCTGAGCGCCTGTTGAACCCACGGGTGCCCGCATCGCAACTACATGGACGCAAAGACCAATACAAAATAA
AGCTCCGTGGCGCAGGCTACCGACTGGTTTACAGTGTCAACGATGATGTTGTGACGGTCACCGTAATTGGCGTCGGTAAA
CGTGAGAATGATGATATTTACAATTTAACCAAACACAGAAATTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9021.01 Da        Isoelectric Point: 5.6864

>AT215162 WP_076841742.1 NZ_CP082807:1920605-1920850 [Burkholderia contaminans]
MSQNASVSRRDHFAELVDTQVQSEQYGSASDVERTGLRLLESRDMQVRALQEALKAGEVSGALRPFDREAFLARMRAAHD
G

Download         Length: 246 bp

>AT215162 NZ_CP110515:234824-235072 [Klebsiella pneumoniae]
ATGGCATTTCAGGTACTAACCACTACTGCAGCAAGCATCACAGAGCTTAAACGTGATCCTATGGGCACTTTCAATGCAGG
AGAAGGTGCCCCTGTAGCCATACTGAATCGCAACGAACCCGCTTTTTACTGTGTACCGCCTGCTCTGTATGCTCAACTGA
TGGAGCTTCTTGAAGATCAGGAGCTGGGTCGTATTGCTGATGAGCGAATTGGTGAGGCGGTAATCGAGGTCAGTCTAGAT
GACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References