Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2114680..2114825 Replicon chromosome
Accession NZ_CP082805
Organism Klebsiella pneumoniae strain SCAID PHRX1-2021 (13/97)

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2114716..2114818 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2114680..2114825 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8B74_RS10175 2109810..2111870 + 2061 WP_004151449.1 oligopeptidase B -
K8B74_RS10180 2111874..2112533 - 660 WP_002911407.1 exodeoxyribonuclease X -
K8B74_RS10185 2112612..2112842 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K8B74_RS10190 2112955..2113329 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K8B74_RS10195 2113333..2114202 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
K8B74_RS10200 2114219..2114557 + 339 WP_002911404.1 YebY family protein -
- 2114680..2114825 - 146 - - Antitoxin
- 2114716..2114818 + 103 - - Toxin
K8B74_RS10205 2115193..2115336 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K8B74_RS10210 2115441..2116409 - 969 WP_014907334.1 VirK/YbjX family protein -
K8B74_RS10215 2116566..2117219 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K8B74_RS10220 2117216..2117407 - 192 WP_002911395.1 YebW family protein -
K8B74_RS10225 2117505..2117744 - 240 WP_002911393.1 YebV family protein -
K8B74_RS10230 2117860..2119293 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T215145 NZ_CP082805:2114716-2114818 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT215145 NZ_CP082805:c2114825-2114680 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References