Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1-Phd |
Location | 647471..648182 | Replicon | chromosome |
Accession | NC_007908 | ||
Organism | Albidiferax ferrireducens T118 (Rhodoferax ferrireducens T118) |
Toxin (Protein)
Gene name | vapC | Uniprot ID | Q221C8 |
Locus tag | RFER_RS03105 | Protein ID | WP_011462948.1 |
Coordinates | 647757..648182 (+) | Length | 142 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | Q221C9 |
Locus tag | RFER_RS03100 | Protein ID | WP_011462947.1 |
Coordinates | 647471..647755 (+) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
RFER_RS03085 | 644055..645221 | + | 1167 | WP_011462944.1 | tricarballylate utilization 4Fe-4S protein TcuB | - |
RFER_RS03090 | 645295..645999 | + | 705 | WP_011462945.1 | hypothetical protein | - |
RFER_RS03095 | 646032..647315 | + | 1284 | WP_011462946.1 | FIST C-terminal domain-containing protein | - |
RFER_RS03100 | 647471..647755 | + | 285 | WP_011462947.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
RFER_RS03105 | 647757..648182 | + | 426 | WP_011462948.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
RFER_RS03110 | 648304..648714 | - | 411 | WP_166485797.1 | hypothetical protein | - |
RFER_RS03115 | 648806..650023 | - | 1218 | WP_011462950.1 | tRNA guanosine(34) transglycosylase Tgt | - |
RFER_RS03120 | 650058..651320 | - | 1263 | WP_011462951.1 | HD domain-containing protein | - |
RFER_RS03125 | 651353..652435 | - | 1083 | WP_011462952.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
RFER_RS03130 | 652621..653016 | + | 396 | WP_011462953.1 | universal stress protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 142 a.a. Molecular weight: 15708.21 Da Isoelectric Point: 5.7559
>T21506 WP_011462948.1 NC_007908:647757-648182 [Rhodoferax ferrireducens T118]
MAVLTGYLLDTNVISETVRAAPDPSVMRWLDSLEPEQLYVSVLSLGEIRKGALAVADKRRRDKLLAWLHNKLPEWFENRV
LPIDAAVCERWADLMVKAGTPTPAIDSLLAATAAHAGLVVATRNVRDFVRLEVGVFNPWEF
MAVLTGYLLDTNVISETVRAAPDPSVMRWLDSLEPEQLYVSVLSLGEIRKGALAVADKRRRDKLLAWLHNKLPEWFENRV
LPIDAAVCERWADLMVKAGTPTPAIDSLLAATAAHAGLVVATRNVRDFVRLEVGVFNPWEF
Download Length: 426 bp
>T21506 NC_007908:647757-648182 [Rhodoferax ferrireducens T118]
ATGGCGGTCCTTACCGGTTATCTGCTCGACACCAACGTCATTTCTGAAACCGTACGCGCCGCACCTGACCCCAGCGTGAT
GCGTTGGCTTGACAGCCTGGAGCCGGAGCAACTGTATGTGAGTGTTCTGAGCCTGGGCGAAATCCGCAAGGGCGCGCTGG
CTGTGGCCGACAAGCGTCGCCGCGACAAGCTGCTGGCCTGGCTGCACAACAAACTGCCCGAGTGGTTTGAAAACCGTGTG
TTGCCGATTGACGCGGCGGTGTGTGAACGCTGGGCCGACTTGATGGTGAAAGCGGGAACTCCCACGCCCGCGATCGACAG
CTTGCTGGCCGCCACGGCGGCCCACGCGGGCCTGGTGGTGGCAACGCGCAATGTGCGCGACTTTGTGCGGTTGGAGGTGG
GGGTTTTCAATCCTTGGGAGTTTTAA
ATGGCGGTCCTTACCGGTTATCTGCTCGACACCAACGTCATTTCTGAAACCGTACGCGCCGCACCTGACCCCAGCGTGAT
GCGTTGGCTTGACAGCCTGGAGCCGGAGCAACTGTATGTGAGTGTTCTGAGCCTGGGCGAAATCCGCAAGGGCGCGCTGG
CTGTGGCCGACAAGCGTCGCCGCGACAAGCTGCTGGCCTGGCTGCACAACAAACTGCCCGAGTGGTTTGAAAACCGTGTG
TTGCCGATTGACGCGGCGGTGTGTGAACGCTGGGCCGACTTGATGGTGAAAGCGGGAACTCCCACGCCCGCGATCGACAG
CTTGCTGGCCGCCACGGCGGCCCACGCGGGCCTGGTGGTGGCAACGCGCAATGTGCGCGACTTTGTGCGGTTGGAGGTGG
GGGTTTTCAATCCTTGGGAGTTTTAA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10334.72 Da Isoelectric Point: 11.1414
>AT21506 WP_011462947.1 NC_007908:647471-647755 [Rhodoferax ferrireducens T118]
MNPSTSHPSSTWQLQDAKAQFSAVVRQAETSGPQLISVRGKPAVVVLSNADYRRLQARSNKPGFTQLMRSSPLVGLDLAV
DRSQDLTRQITLEK
MNPSTSHPSSTWQLQDAKAQFSAVVRQAETSGPQLISVRGKPAVVVLSNADYRRLQARSNKPGFTQLMRSSPLVGLDLAV
DRSQDLTRQITLEK
Download Length: 285 bp
>AT21506 NC_007908:647471-647755 [Rhodoferax ferrireducens T118]
ATGAATCCATCCACGTCCCATCCATCGTCAACCTGGCAGCTTCAGGATGCCAAGGCTCAGTTCAGCGCCGTGGTCCGGCA
GGCTGAAACCAGCGGGCCACAACTCATCAGTGTGCGCGGCAAGCCGGCCGTGGTGGTGCTCTCCAATGCGGACTACCGGC
GGCTGCAAGCTCGCTCCAACAAACCCGGTTTTACGCAGTTGATGCGGAGTTCGCCGCTGGTTGGACTGGATTTGGCCGTC
GATCGAAGCCAGGACCTCACGCGCCAGATCACGCTGGAGAAATGA
ATGAATCCATCCACGTCCCATCCATCGTCAACCTGGCAGCTTCAGGATGCCAAGGCTCAGTTCAGCGCCGTGGTCCGGCA
GGCTGAAACCAGCGGGCCACAACTCATCAGTGTGCGCGGCAAGCCGGCCGTGGTGGTGCTCTCCAATGCGGACTACCGGC
GGCTGCAAGCTCGCTCCAACAAACCCGGTTTTACGCAGTTGATGCGGAGTTCGCCGCTGGTTGGACTGGATTTGGCCGTC
GATCGAAGCCAGGACCTCACGCGCCAGATCACGCTGGAGAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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