Detailed information of TA system TA021504

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higB-toxA/Tad-couple_hipB
• Location: 4177892..4178394
• Replicon: chromosome
• Accession: NC_007907
• Organism: Desulfitobacterium hafniense Y51

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: DSY_RS19500
• Protein ID: WP_080510925.1
• Coordinates: 4177892..4178086 (+)
• Length: 65 a.a.

Antitoxin (Protein)

• Gene name: toxA
• Uniprot ID: -
• Locus tag: DSY_RS19505
• Protein ID: WP_011461278.1
• Coordinates: 4178083..4178394 (+)
• Length: 104 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DSY_RS19490	4174641..4175174	-	534	WP_041272570.1	hypothetical protein	-
DSY_RS19495	4175473..4177581	+	2109	WP_041272571.1	FAD-binding protein	-
DSY_RS19500	4177892..4178086	+	195	WP_080510925.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
DSY_RS19505	4178083..4178394	+	312	WP_011461278.1	helix-turn-helix domain-containing protein	Antitoxin
DSY_RS19510	4178500..4180209	-	1710	WP_011461279.1	adenine deaminase	-
DSY_RS19520	4180880..4181371	+	492	WP_011461280.1	GNAT family N-acetyltransferase	-
DSY_RS19525	4181706..4182161	+	456	WP_011461281.1	Hsp20/alpha crystallin family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (7-55)

Antitoxin

• Cro/C1-type helix-turn-helix domain (42-93)

Sequences

Toxin

Protein

• Length: 65 a.a.
• Molecular weight: 8029.22 Da
• Isoelectric Point: 8.0275

>T21504 WP_080510925.1 NC_007907:4177892-4178086 [Desulfitobacterium hafniense Y51]
ICYYTIGDLWELRPLENRIFFFYWRDNTFVLLHHFIKKSQKTPTKEIEQARTNLKDFLERFDDK

Nucleotide

• Length: 195 bp

>T21504 NC_007907:4177892-4178086 [Desulfitobacterium hafniense Y51]
ATATGTTATTATACTATTGGGGATTTGTGGGAATTGCGACCACTTGAAAACCGTATCTTTTTCTTCTACTGGCGTGACAA
TACTTTTGTACTGCTCCACCACTTTATCAAGAAAAGCCAAAAAACGCCGACAAAAGAAATAGAGCAAGCCAGAACTAACC
TAAAGGACTTTTTAGAAAGGTTTGATGATAAATGA

Antitoxin

Protein

• Length: 104 a.a.
• Molecular weight: 11294.12 Da
• Isoelectric Point: 5.8150

>AT21504 WP_011461278.1 NC_007907:4178083-4178394 [Desulfitobacterium hafniense Y51]
MSVKIGNTNFTEFNDLYNDPNIVPPAERAKIDFEVALIGKLIEAREAKGLSQKQLADLAGLKQPAIARLESMKATPQIDT
LFKILHPLGYTLAVVPVDPPQQP

Nucleotide

• Length: 312 bp

>AT21504 NC_007907:4178083-4178394 [Desulfitobacterium hafniense Y51]
ATGAGCGTTAAAATAGGAAACACTAATTTCACAGAATTTAATGACTTGTATAATGACCCTAATATCGTCCCCCCCGCTGA
ACGTGCTAAAATTGATTTTGAAGTAGCGTTAATCGGAAAGCTGATAGAGGCTAGGGAAGCAAAGGGACTGTCACAAAAAC
AGCTGGCAGATCTGGCCGGATTAAAGCAACCCGCTATAGCCAGGCTGGAAAGCATGAAGGCGACACCCCAAATTGATACC
CTTTTCAAAATCTTACACCCTTTGGGATATACTTTGGCTGTAGTCCCTGTCGATCCCCCGCAGCAGCCGTAG