Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-DinJ
Location 1123970..1124500 Replicon chromosome
Accession NC_007907
Organism Desulfitobacterium hafniense Y51

Toxin (Protein)


Gene name yoeB Uniprot ID G9XQY7
Locus tag DSY_RS05060 Protein ID WP_005813975.1
Coordinates 1124237..1124500 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G9XQY6
Locus tag DSY_RS05055 Protein ID WP_005813972.1
Coordinates 1123970..1124233 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSY_RS05025 1119923..1120381 + 459 WP_005813957.1 MarR family transcriptional regulator -
DSY_RS05030 1120494..1121057 + 564 WP_011459439.1 nitroreductase -
DSY_RS05035 1121172..1121594 - 423 WP_005813961.1 HIT family protein -
DSY_RS05040 1122230..1122538 - 309 WP_005813967.1 helix-turn-helix domain-containing protein -
DSY_RS05045 1122679..1122903 + 225 WP_005813969.1 hypothetical protein -
DSY_RS05050 1122997..1123869 + 873 WP_005813971.1 hypothetical protein -
DSY_RS05055 1123970..1124233 + 264 WP_005813972.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DSY_RS05060 1124237..1124500 + 264 WP_005813975.1 Txe/YoeB family addiction module toxin Toxin
DSY_RS05065 1124703..1125110 + 408 WP_005813977.1 type II toxin-antitoxin system HicB family antitoxin -
DSY_RS05070 1125493..1128918 + 3426 WP_005813980.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(6-60)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10316.75 Da        Isoelectric Point: 9.4632

>T21501 WP_005813975.1 NC_007907:1124237-1124500 [Desulfitobacterium hafniense Y51]
MKKLWTDQAWADYLYWQSQDKKTLRRINQLLLDIEHNGYDGIGKPEQLRGDLTGWCSRRIDNTNRLVYRMTDGIIVIASC
RTHYGNK

Download         Length: 264 bp

>T21501 NC_007907:1124237-1124500 [Desulfitobacterium hafniense Y51]
ATGAAAAAGTTATGGACTGACCAAGCCTGGGCAGACTACCTGTACTGGCAAAGTCAAGATAAAAAAACGCTGAGAAGAAT
AAATCAACTTTTACTGGATATTGAGCACAATGGTTATGATGGAATTGGTAAACCGGAACAGTTGCGCGGCGATTTAACCG
GGTGGTGTTCCCGCCGTATCGATAACACGAACCGGCTTGTCTATCGTATGACTGATGGGATAATCGTTATAGCAAGCTGT
CGTACGCATTATGGTAATAAATAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9852.12 Da        Isoelectric Point: 4.5026

>AT21501 WP_005813972.1 NC_007907:1123970-1124233 [Desulfitobacterium hafniense Y51]
MAETTNLNIRIDKELKEQAEAFFNELGLNMTTAFNIFVRQSLRQGGIPFDITLNTDGFYNPTNMKMLRQSIQDANEGKLT
AHDLLGD

Download         Length: 264 bp

>AT21501 NC_007907:1123970-1124233 [Desulfitobacterium hafniense Y51]
ATGGCTGAAACGACCAACTTGAATATCCGGATTGATAAAGAGCTGAAAGAGCAGGCTGAAGCGTTTTTCAATGAGTTAGG
CTTGAATATGACAACGGCGTTTAATATTTTTGTGCGGCAATCCCTTCGCCAAGGTGGAATACCTTTTGATATTACGTTGA
ATACGGATGGTTTTTATAACCCAACGAATATGAAAATGCTACGACAATCCATTCAGGATGCCAACGAAGGTAAGTTGACC
GCTCATGATTTACTTGGTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0W1JJJ9

Antitoxin

Source ID Structure
AlphaFold DB A0A098B6U4

References