Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2903109..2903377 Replicon chromosome
Accession NZ_CP082777
Organism Escherichia coli O25:H1 strain CU39ES-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2903147..2903249 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2903109..2903377 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8B91_RS14240 2900266..2901705 + 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
K8B91_RS14245 2901823..2902059 + 237 WP_001295499.1 YebV family protein -
K8B91_RS14250 2902164..2902355 + 192 WP_001317886.1 YebW family protein -
K8B91_RS14255 2902356..2903012 - 657 WP_000812743.1 protein-serine/threonine phosphatase -
- 2903109..2903377 + 269 - - Antitoxin
- 2903147..2903249 - 103 - - Toxin
K8B91_RS14260 2903407..2903748 - 342 WP_000984819.1 YebY family protein -
K8B91_RS14265 2903761..2904633 - 873 WP_000879311.1 copper homeostasis membrane protein CopD -
K8B91_RS14270 2904637..2905011 - 375 WP_000168747.1 CopC domain-containing protein YobA -
K8B91_RS14275 2905150..2905380 + 231 WP_000916763.1 DNA polymerase III subunit theta -
K8B91_RS14280 2905483..2906139 + 657 WP_000011644.1 carbon-nitrogen hydrolase family protein YobB -
K8B91_RS14285 2906163..2906825 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T215003 NZ_CP082777:c2903249-2903147 [Escherichia coli O25:H1]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT215003 NZ_CP082777:2903109-2903377 [Escherichia coli O25:H1]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References