Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2776493..2776761 Replicon chromosome
Accession NZ_CP082775
Organism Escherichia coli O25:H4 strain CU568-3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2776531..2776633 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2776493..2776761 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8B89_RS13935 2773651..2775090 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
K8B89_RS13940 2775207..2775443 + 237 WP_001295499.1 YebV family protein -
K8B89_RS13945 2775548..2775739 + 192 WP_001296140.1 YebW family protein -
K8B89_RS13950 2775740..2776396 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 2776493..2776761 + 269 - - Antitoxin
- 2776531..2776633 - 103 - - Toxin
K8B89_RS13955 2776791..2777132 - 342 WP_000976472.1 YebY family protein -
K8B89_RS13960 2777145..2778017 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
K8B89_RS13965 2778021..2778395 - 375 WP_000168747.1 CopC domain-containing protein YobA -
K8B89_RS13970 2778534..2778764 + 231 WP_000916763.1 DNA polymerase III subunit theta -
K8B89_RS13975 2778866..2779522 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
K8B89_RS13980 2779546..2780208 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T214953 NZ_CP082775:c2776633-2776531 [Escherichia coli O25:H4]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT214953 NZ_CP082775:2776493-2776761 [Escherichia coli O25:H4]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References