Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2745031..2745299 Replicon chromosome
Accession NZ_CP082773
Organism Escherichia coli O99:H6 strain CU42ET-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2745069..2745171 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2745031..2745299 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8B87_RS13295 2742188..2743627 + 1440 WP_001313925.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
K8B87_RS13300 2743745..2743981 + 237 WP_001295499.1 YebV family protein -
K8B87_RS13305 2744086..2744277 + 192 WP_001317886.1 YebW family protein -
K8B87_RS13310 2744278..2744934 - 657 WP_000812742.1 protein-serine/threonine phosphatase -
- 2745031..2745299 + 269 - - Antitoxin
- 2745069..2745171 - 103 - - Toxin
K8B87_RS13315 2745329..2745670 - 342 WP_000976472.1 YebY family protein -
K8B87_RS13320 2745683..2746555 - 873 WP_000879320.1 copper homeostasis membrane protein CopD -
K8B87_RS13325 2746559..2746933 - 375 WP_000168747.1 CopC domain-containing protein YobA -
K8B87_RS13330 2747072..2747302 + 231 WP_000916763.1 DNA polymerase III subunit theta -
K8B87_RS13335 2747404..2748060 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
K8B87_RS13340 2748083..2748745 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T214898 NZ_CP082773:c2745171-2745069 [Escherichia coli O99:H6]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT214898 NZ_CP082773:2745031-2745299 [Escherichia coli O99:H6]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References