Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014445..2014590 Replicon chromosome
Accession NZ_CP082765
Organism Klebsiella pneumoniae strain 12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014481..2014583 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014445..2014590 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FTO26_RS09840 (FTO26_009840) 2009575..2011635 + 2061 WP_004151449.1 oligopeptidase B -
FTO26_RS09845 (FTO26_009845) 2011639..2012298 - 660 WP_002911407.1 exodeoxyribonuclease X -
FTO26_RS09850 (FTO26_009850) 2012377..2012607 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FTO26_RS09855 (FTO26_009855) 2012720..2013094 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FTO26_RS09860 (FTO26_009860) 2013098..2013967 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
FTO26_RS09865 (FTO26_009865) 2013984..2014322 + 339 WP_002911404.1 YebY family protein -
- 2014445..2014590 - 146 - - Antitoxin
- 2014481..2014583 + 103 - - Toxin
FTO26_RS09870 (FTO26_009870) 2014958..2015101 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FTO26_RS09875 (FTO26_009875) 2015206..2016174 - 969 WP_004151446.1 VirK/YbjX family protein -
FTO26_RS09880 (FTO26_009880) 2016331..2016984 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
FTO26_RS09885 (FTO26_009885) 2016981..2017172 - 192 WP_002911395.1 YebW family protein -
FTO26_RS09890 (FTO26_009890) 2017270..2017509 - 240 WP_002911393.1 YebV family protein -
FTO26_RS09895 (FTO26_009895) 2017625..2019058 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T214801 NZ_CP082765:2014481-2014583 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT214801 NZ_CP082765:c2014590-2014445 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References