Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014262..2014407 Replicon chromosome
Accession NZ_CP082759
Organism Klebsiella pneumoniae strain 36

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014298..2014400 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014262..2014407 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FTO14_RS09855 (FTO14_009855) 2009392..2011452 + 2061 WP_004151449.1 oligopeptidase B -
FTO14_RS09860 (FTO14_009860) 2011456..2012115 - 660 WP_002911407.1 exodeoxyribonuclease X -
FTO14_RS09865 (FTO14_009865) 2012194..2012424 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FTO14_RS09870 (FTO14_009870) 2012537..2012911 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FTO14_RS09875 (FTO14_009875) 2012915..2013784 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
FTO14_RS09880 (FTO14_009880) 2013801..2014139 + 339 WP_002911404.1 YebY family protein -
- 2014262..2014407 - 146 - - Antitoxin
- 2014298..2014400 + 103 - - Toxin
FTO14_RS09885 (FTO14_009885) 2014775..2014918 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FTO14_RS09890 (FTO14_009890) 2015023..2015991 - 969 WP_004151446.1 VirK/YbjX family protein -
FTO14_RS09895 (FTO14_009895) 2016148..2016801 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
FTO14_RS09900 (FTO14_009900) 2016798..2016989 - 192 WP_002911395.1 YebW family protein -
FTO14_RS09905 (FTO14_009905) 2017087..2017326 - 240 WP_002911393.1 YebV family protein -
FTO14_RS09910 (FTO14_009910) 2017442..2018875 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T214774 NZ_CP082759:2014298-2014400 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT214774 NZ_CP082759:c2014407-2014262 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References