Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2013487..2013632 Replicon chromosome
Accession NZ_CP082753
Organism Klebsiella pneumoniae strain 37

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2013523..2013625 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2013487..2013632 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FTO11_RS09850 (FTO11_009850) 2008617..2010677 + 2061 WP_004151449.1 oligopeptidase B -
FTO11_RS09855 (FTO11_009855) 2010681..2011340 - 660 WP_002911407.1 exodeoxyribonuclease X -
FTO11_RS09860 (FTO11_009860) 2011419..2011649 - 231 WP_002911406.1 DNA polymerase III subunit theta -
FTO11_RS09865 (FTO11_009865) 2011762..2012136 + 375 WP_004151448.1 CopC domain-containing protein YobA -
FTO11_RS09870 (FTO11_009870) 2012140..2013009 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
FTO11_RS09875 (FTO11_009875) 2013026..2013364 + 339 WP_002911404.1 YebY family protein -
- 2013487..2013632 - 146 - - Antitoxin
- 2013523..2013625 + 103 - - Toxin
FTO11_RS09880 (FTO11_009880) 2014000..2014143 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
FTO11_RS09885 (FTO11_009885) 2014248..2015216 - 969 WP_004151446.1 VirK/YbjX family protein -
FTO11_RS09890 (FTO11_009890) 2015373..2016026 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
FTO11_RS09895 (FTO11_009895) 2016023..2016214 - 192 WP_002911395.1 YebW family protein -
FTO11_RS09900 (FTO11_009900) 2016312..2016551 - 240 WP_002911393.1 YebV family protein -
FTO11_RS09905 (FTO11_009905) 2016667..2018100 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T214747 NZ_CP082753:2013523-2013625 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT214747 NZ_CP082753:c2013632-2013487 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References