Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-GNAT
Location 4804287..4805106 Replicon chromosome
Accession NZ_CP082360
Organism Klebsiella sp. CTHL.F3a

Toxin (Protein)


Gene name yjhX Uniprot ID -
Locus tag K7H21_RS22570 Protein ID WP_004129235.1
Coordinates 4804849..4805106 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag K7H21_RS22565 Protein ID WP_004129242.1
Coordinates 4804287..4804838 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7H21_RS22545 (K7H21_22545) 4799924..4800688 + 765 WP_154902344.1 SDR family NAD(P)-dependent oxidoreductase -
K7H21_RS22550 (K7H21_22550) 4800736..4801155 + 420 WP_049115076.1 RbsD/FucU family protein -
K7H21_RS22555 (K7H21_22555) 4801199..4802245 - 1047 WP_004129248.1 LacI family DNA-binding transcriptional regulator -
K7H21_RS29085 4802641..4803387 - 747 WP_117085590.1 class I SAM-dependent methyltransferase -
K7H21_RS29090 4803814..4804173 - 360 Protein_4446 class I SAM-dependent methyltransferase -
K7H21_RS22565 (K7H21_22565) 4804287..4804838 - 552 WP_004129242.1 N-acetyltransferase Antitoxin
K7H21_RS22570 (K7H21_22570) 4804849..4805106 - 258 WP_004129235.1 YjhX family toxin Toxin
K7H21_RS22575 (K7H21_22575) 4805690..4806874 + 1185 WP_049115080.1 mannonate dehydratase -
K7H21_RS22580 (K7H21_22580) 4806951..4808426 + 1476 WP_112165899.1 fructuronate reductase -
K7H21_RS22585 (K7H21_22585) 4808564..4809340 + 777 WP_172879943.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9568.07 Da        Isoelectric Point: 11.1381

>T214737 WP_004129235.1 NZ_CP082360:c4805106-4804849 [Klebsiella sp. CTHL.F3a]
MNLSRQEQRTLHVLAKGGRIAHVRDTSGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T214737 NZ_CP110201:881288-881686 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGCTGAAATTCATGCTTGATACCAATACCTGTATTTTCACCATCAAAAATAAGCCCGAACACATCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCGCCGG
AGCGTAATCTTGCCGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTTTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTGCCGAACTGGCCCGCAAGGGAACACCTGTCGGGCCTTATGACCAGATGATTGCTGGCCATGCCGGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAATTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20041.90 Da        Isoelectric Point: 7.5404

>AT214737 WP_004129242.1 NZ_CP082360:c4804838-4804287 [Klebsiella sp. CTHL.F3a]
MTNHSFTFHVASEGDTDDILNVETRAFGYSKEARLVASLLNDESASPTLSLLARHNGKAVGHILFTRAMFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGALIRHGIEQLKAMGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYSIPEAHKACWMLQRLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT214737 NZ_CP110201:881061-881288 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGCACACAACACTTTTTTTTAGTAACCGGACCCAGGCAGTCAGATTGCCTAAATCGATATCCTTTCCGGAGGATGTGAA
ACATGTCGAAATCATTGCGGTTGGCAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGGACAGCTGGTTCGATGGCG
AAGGCGCCAGTACTGATTTTATGAGTACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References