Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 1366495..1367044 Replicon chromosome
Accession NZ_CP082317
Organism Vibrio alginolyticus strain SXV3

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag K6754_RS06705 Protein ID WP_045369102.1
Coordinates 1366495..1366794 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag K6754_RS06710 Protein ID WP_238975189.1
Coordinates 1366802..1367044 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6754_RS06670 (K6754_06640) 1361859..1363022 + 1164 WP_238975180.1 hypothetical protein -
K6754_RS06675 (K6754_06645) 1363158..1363565 + 408 WP_238975182.1 DUF1330 domain-containing protein -
K6754_RS06680 (K6754_06650) 1363734..1364234 + 501 WP_238975184.1 opioid growth factor receptor-related protein -
K6754_RS06685 (K6754_06655) 1364276..1364365 + 90 WP_072609597.1 DUF3265 domain-containing protein -
K6754_RS06690 (K6754_06660) 1364413..1365468 + 1056 WP_238975186.1 PIN domain-containing protein -
K6754_RS06695 (K6754_06665) 1365488..1365580 + 93 WP_130361595.1 DUF3265 domain-containing protein -
K6754_RS06700 (K6754_06670) 1365653..1366312 + 660 WP_238975188.1 CatB-related O-acetyltransferase -
K6754_RS06705 (K6754_06675) 1366495..1366794 - 300 WP_045369102.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K6754_RS06710 (K6754_06680) 1366802..1367044 - 243 WP_238975189.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
K6754_RS06715 (K6754_06685) 1367158..1367247 + 90 WP_072612536.1 DUF3265 domain-containing protein -
K6754_RS06720 (K6754_06690) 1367287..1367775 + 489 WP_238975191.1 HAD-IIIA family hydrolase -
K6754_RS06725 1367736..1367828 + 93 Protein_1244 DUF3265 domain-containing protein -
K6754_RS06730 (K6754_06695) 1368401..1368490 + 90 WP_072612536.1 DUF3265 domain-containing protein -
K6754_RS06735 (K6754_06700) 1368824..1368934 + 111 WP_238975300.1 DUF3265 domain-containing protein -
K6754_RS06740 (K6754_06705) 1368961..1369368 + 408 WP_238975193.1 hypothetical protein -
K6754_RS06745 (K6754_06710) 1369397..1369486 + 90 WP_072615095.1 DUF3265 domain-containing protein -
K6754_RS06750 (K6754_06715) 1369508..1369771 + 264 WP_045421363.1 hypothetical protein -
K6754_RS06755 (K6754_06720) 1369794..1369886 + 93 WP_071936844.1 DUF3265 domain-containing protein -
K6754_RS06760 (K6754_06725) 1369913..1370641 + 729 WP_238969959.1 DUF5677 domain-containing protein -
K6754_RS06765 (K6754_06730) 1370832..1371140 + 309 WP_004413754.1 transposase -
K6754_RS06770 (K6754_06735) 1371137..1371988 + 852 WP_053307556.1 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1316682..1376441 59759
- inside Integron - - 1317199..1373707 56508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11524.16 Da        Isoelectric Point: 9.6267

>T214555 WP_045369102.1 NZ_CP082317:c1366794-1366495 [Vibrio alginolyticus]
MQKNKYKLSNLAQSHLRKVKNYTVENFSELQWRNYKDTLLSGFQMLADNPGLGRSCHELYPNGFYFPIGKHTAYFTKEDD
FILVVAVLGQSQLPQNHLK

Download         Length: 300 bp

>T214555 NZ_CP110141:c1293829-1293041 [Streptococcus suis]
ATGAGATTGGAAGAATTTAGTGAGGTAGAGTTTCAGAAGGCCTTACAGCGAACCATTCGGGCTTTAACTCGAGGAAAGAC
GATTCCAGATCAACCGAAAGCCATTTTACTTGGAGGTCAGAGCGGAGCAGGTAAGACAACGATACATCGTATCAAGCAAA
AAGAATTTCAAGGCAATATCATTATCATCGATGGTGACAGCTACCGTTCTCAGCATCCCAATTACTTAGCCTTGCAAGAA
AAGTATGGCAAAGATAGCGTGGACTATACCAAGGGATTTGCAGGAAAGATGGTAGAACATCTGGTTGATGAACTCAGTAA
ACGTGGTTATCATTTGTTAATTGAAGGGACTTTGCGTACCACTCAAGTTCCTCGTCAGACTGCTCAATTATTAACTTCTA
AAGGTTACCAAGTTTCTTTAGCTATTATTGGTACCAAACCAGAACTGTCCTATCTCAGCACCTTGATTCGTTACGAAGAG
CTTTATGCCATCGATCCGACGCAGGCCAGAGCAACACCCAAAGACCACCATGATGGGATTGTAGAGAACTTGGTTGATAA
CCTAAGAGAGTTAGAAAGAGAGCAACTCTTTGACCAGATTCAGATTTATCAAAGAGATAGGGCTTGTATCTATGATTCTG
AAACGGATGAAGGTTCCGCAGCAGAAGTTCTACAAGACTGCCTCTTTGGAAAATGTAGTAAGGTTGAGGAAGAGATGATG
AAGTTAGGTCGGGAACGGTTAGTTAAACTGAATAATAAGAATTTGCTGGAGAGTAACTATGGAATTTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9073.29 Da        Isoelectric Point: 5.1051

>AT214555 WP_238975189.1 NZ_CP082317:c1367044-1366802 [Vibrio alginolyticus]
MYTLTANDAKRNFGELLLSAQREPVKISKNSKDTVVVMSIRDFEELEAMKVEYLKHCFKSAKEDLNNGNTVDGESFINSL

Download         Length: 243 bp

>AT214555 NZ_CP110141:c1294305-1293829 [Streptococcus suis]
ATGATTGGAGACAATATTAAATCACTACGCCGAACACACGATTTAACACAACCAGAATTTGCGAAAATGGTCGGGATTTC
ACGCAATAGCCTGAGTCGCTACGAAAATGGAACCAGCACCGTTTCAACAGAACTCATTGACCGCATTTGTCAGAAATTTA
ACGTTTCTTATGTCGATATTGTAGGAGAGGACAAGATGCTAACACCTGTTGAAGATTACCAACTGACTTTAAAAATAGAA
GTGATAAAAGAACGTGGAGCAGCCATTTTATCTCAACTCTATCGATATCAGGATAGTCAAGGTATTGCTTTTGATGATGA
AACAAATCCTTGGATTTTGATGAGTGATGATTTGGCTGAATTGATCAATACGAAAATATACCTTGTCGATACTTTCGATG
AAATAGAGCGTTACAATGGCTATTTAGACGGTATCGAGCGGATGTTAGACATGGTGCATCATCGGGTGGTGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References