Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafN(antitoxin) |
| Location | 1336681..1337246 | Replicon | chromosome |
| Accession | NZ_CP082317 | ||
| Organism | Vibrio alginolyticus strain SXV3 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | K6754_RS06365 | Protein ID | WP_238975161.1 |
| Coordinates | 1336959..1337246 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | U3BLE1 |
| Locus tag | K6754_RS06360 | Protein ID | WP_000086647.1 |
| Coordinates | 1336681..1336962 (+) | Length | 94 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6754_RS06315 (K6754_06300) | 1332372..1333022 | + | 651 | WP_238975156.1 | hypothetical protein | - |
| K6754_RS06320 (K6754_06305) | 1333046..1333135 | + | 90 | WP_079858407.1 | DUF3265 domain-containing protein | - |
| K6754_RS06325 (K6754_06310) | 1333754..1334242 | + | 489 | WP_238975157.1 | DUF523 domain-containing protein | - |
| K6754_RS06330 (K6754_06315) | 1334260..1334349 | + | 90 | WP_071881309.1 | DUF3265 domain-containing protein | - |
| K6754_RS06335 (K6754_06320) | 1334403..1334699 | - | 297 | WP_029807603.1 | hypothetical protein | - |
| K6754_RS06340 (K6754_06325) | 1335263..1335355 | + | 93 | WP_202801016.1 | DUF3265 domain-containing protein | - |
| K6754_RS06345 (K6754_06330) | 1335777..1335959 | - | 183 | WP_238975159.1 | hypothetical protein | - |
| K6754_RS06350 (K6754_06335) | 1335959..1336414 | - | 456 | WP_176289436.1 | hypothetical protein | - |
| K6754_RS06355 (K6754_06340) | 1336498..1336590 | + | 93 | WP_238975302.1 | DUF3265 domain-containing protein | - |
| K6754_RS06360 (K6754_06345) | 1336681..1336962 | + | 282 | WP_000086647.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| K6754_RS06365 (K6754_06350) | 1336959..1337246 | + | 288 | WP_238975161.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| K6754_RS06370 (K6754_06355) | 1337399..1337992 | + | 594 | WP_238975162.1 | hypothetical protein | - |
| K6754_RS06375 (K6754_06360) | 1338007..1338099 | + | 93 | WP_124009230.1 | DUF3265 domain-containing protein | - |
| K6754_RS06380 (K6754_06365) | 1338136..1338717 | + | 582 | WP_238975164.1 | DJ-1/PfpI family protein | - |
| K6754_RS06385 (K6754_06370) | 1338740..1338832 | + | 93 | WP_078532130.1 | DUF3265 domain-containing protein | - |
| K6754_RS06390 (K6754_06375) | 1338861..1339388 | + | 528 | WP_238975166.1 | CbrC family protein | - |
| K6754_RS06395 | 1339352..1339447 | + | 96 | Protein_1179 | DUF3265 domain-containing protein | - |
| K6754_RS06400 (K6754_06380) | 1339543..1339860 | + | 318 | Protein_1180 | cytidine deaminase | - |
| K6754_RS06405 (K6754_06385) | 1339881..1339973 | + | 93 | WP_080607093.1 | DUF3265 domain-containing protein | - |
| K6754_RS06410 (K6754_06390) | 1340456..1340583 | + | 128 | Protein_1182 | DUF3265 domain-containing protein | - |
| K6754_RS06415 (K6754_06395) | 1340615..1341112 | + | 498 | WP_049874847.1 | hypothetical protein | - |
| K6754_RS06420 (K6754_06400) | 1341115..1341252 | + | 138 | WP_154216439.1 | hypothetical protein | - |
| K6754_RS06425 (K6754_06405) | 1341267..1341359 | + | 93 | WP_072884142.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1316682..1376441 | 59759 | |
| - | inside | Integron | - | - | 1317199..1373707 | 56508 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11003.69 Da Isoelectric Point: 5.1098
>T214552 WP_238975161.1 NZ_CP082317:1336959-1337246 [Vibrio alginolyticus]
MKVVWSPLALQKLGDAAEFISLDNPPAAEKWVNEVFDKTELLGSMPEMGRFVPEIPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQMLSEDDV
MKVVWSPLALQKLGDAAEFISLDNPPAAEKWVNEVFDKTELLGSMPEMGRFVPEIPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQMLSEDDV
Download Length: 288 bp
>T214552 NZ_CP110141:772902-773162 [Streptococcus suis]
ATGTATCATTTAGAGTATTCTAAAAAGGCTCAAAAGCAAATTAAGAAATTAGATAGGCAAATTCAGAGGTTGTTGTTTGC
TTGGATTGATAAACACTTAGAAGGGACTGATAATCCACGCGCCAATGGTAAAGGTTTGACAGGCAATCATGCTAACGAGT
GGCGTTATCGTATCGGAGATTACCGACTGATTTGCGATATTCAAGATGATAAGTTGGTTATTTTAGCACTTGAGTTTGGA
CATCGTAAAGATGTCTATTGA
ATGTATCATTTAGAGTATTCTAAAAAGGCTCAAAAGCAAATTAAGAAATTAGATAGGCAAATTCAGAGGTTGTTGTTTGC
TTGGATTGATAAACACTTAGAAGGGACTGATAATCCACGCGCCAATGGTAAAGGTTTGACAGGCAATCATGCTAACGAGT
GGCGTTATCGTATCGGAGATTACCGACTGATTTGCGATATTCAAGATGATAAGTTGGTTATTTTAGCACTTGAGTTTGGA
CATCGTAAAGATGTCTATTGA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10398.91 Da Isoelectric Point: 5.8650
>AT214552 WP_000086647.1 NZ_CP082317:1336681-1336962 [Vibrio alginolyticus]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK
Download Length: 282 bp
>AT214552 NZ_CP110141:772679-772900 [Streptococcus suis]
ATGAGTACAGTGACAATCAGATTAAATCAAGAAGAAGAAGTATTCTTTAAAAGCTATGCACAATTAACAGGTCAAAGTCT
TTCTAGCCTTTTTAAGAAAGCTTTGGAGCGTGATATTGAAGATGAGTATGATTTAAAAATCTATCATCAAGCTTATGATG
AGTACAAAGCAGATCCAGAAACAATTAGTCATGCTGATTTTAAGAAAGAGCTAGGATTATAG
ATGAGTACAGTGACAATCAGATTAAATCAAGAAGAAGAAGTATTCTTTAAAAGCTATGCACAATTAACAGGTCAAAGTCT
TTCTAGCCTTTTTAAGAAAGCTTTGGAGCGTGATATTGAAGATGAGTATGATTTAAAAATCTATCATCAAGCTTATGATG
AGTACAAAGCAGATCCAGAAACAATTAGTCATGCTGATTTTAAGAAAGAGCTAGGATTATAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|