Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-RelB |
Location | 1400336..1400895 | Replicon | chromosome |
Accession | NZ_CP082315 | ||
Organism | Vibrio alginolyticus strain ZLV3 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A2I3C6F2 |
Locus tag | K6752_RS06925 | Protein ID | WP_005377065.1 |
Coordinates | 1400336..1400614 (-) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A2I3C6F3 |
Locus tag | K6752_RS06930 | Protein ID | WP_005487956.1 |
Coordinates | 1400611..1400895 (-) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
K6752_RS06860 (K6752_06830) | 1396156..1396249 | + | 94 | Protein_1274 | DUF3265 domain-containing protein | - |
K6752_RS06865 (K6752_06835) | 1396341..1396619 | + | 279 | WP_017633714.1 | hypothetical protein | - |
K6752_RS06870 (K6752_06840) | 1396637..1396726 | + | 90 | WP_081008380.1 | DUF3265 domain-containing protein | - |
K6752_RS06875 (K6752_06845) | 1396759..1397160 | + | 402 | WP_005377049.1 | HIT family protein | - |
K6752_RS06880 (K6752_06850) | 1397195..1397287 | + | 93 | WP_080276993.1 | DUF3265 domain-containing protein | - |
K6752_RS06885 (K6752_06855) | 1397316..1397672 | + | 357 | WP_005377051.1 | hypothetical protein | - |
K6752_RS06890 (K6752_06860) | 1398189..1398326 | + | 138 | WP_081008312.1 | DUF3265 domain-containing protein | - |
K6752_RS06895 (K6752_06865) | 1398356..1398964 | + | 609 | WP_005377053.1 | hypothetical protein | - |
K6752_RS06900 | 1398961..1399077 | + | 117 | WP_081008313.1 | DUF3265 domain-containing protein | - |
K6752_RS06905 (K6752_06870) | 1399127..1399558 | + | 432 | WP_005377056.1 | DUF1851 domain-containing protein | - |
K6752_RS06910 (K6752_06875) | 1399573..1399665 | + | 93 | WP_198136763.1 | DUF3265 domain-containing protein | - |
K6752_RS06915 (K6752_06880) | 1399715..1400185 | + | 471 | WP_005377057.1 | GNAT family N-acetyltransferase | - |
K6752_RS06920 (K6752_06885) | 1400215..1400307 | + | 93 | WP_004749136.1 | DUF3265 domain-containing protein | - |
K6752_RS06925 (K6752_06890) | 1400336..1400614 | - | 279 | WP_005377065.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
K6752_RS06930 (K6752_06895) | 1400611..1400895 | - | 285 | WP_005487956.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
K6752_RS06935 (K6752_06900) | 1401096..1401590 | + | 495 | WP_005377068.1 | GNAT family N-acetyltransferase | - |
K6752_RS06940 | 1401870..1402076 | + | 207 | WP_005377069.1 | hypothetical protein | - |
K6752_RS06945 | 1402083..1402217 | + | 135 | WP_005377070.1 | DUF3265 domain-containing protein | - |
K6752_RS06950 (K6752_06910) | 1402277..1402756 | - | 480 | WP_021033918.1 | hypothetical protein | - |
K6752_RS06955 (K6752_06915) | 1403024..1403545 | + | 522 | WP_005377075.1 | GNAT family N-acetyltransferase | - |
K6752_RS06960 (K6752_06920) | 1403650..1404051 | + | 402 | WP_005377076.1 | DUF2007 domain-containing protein | - |
K6752_RS06965 (K6752_06925) | 1404195..1404803 | + | 609 | WP_005377078.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
K6752_RS06970 (K6752_06930) | 1405017..1405358 | + | 342 | WP_005377079.1 | RDD family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integron | - | - | 1337138..1401877 | 64739 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10905.60 Da Isoelectric Point: 4.3430
>T214551 WP_005377065.1 NZ_CP082315:c1400614-1400336 [Vibrio alginolyticus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIISYWVEGDIIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIISYWVEGDIIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T214551 NZ_CP110141:461393-461650 [Streptococcus suis]
ATGGGAATCCATTTTACAGAGGATGCCTGGGAAGACTATCTTTATTGGCAAGGTCAGGATAAGAAAACACTCAAGCGAAT
CAATAAGATTATCAAGGATATGCAACGACATCCTTTTGAAGGCATTGCCAAACCAGAACCCTTGAAGTATGATTATCAGG
GTGCCTGGTCTCGGAGAATTGATGCCGAAAATCGGCTGATTTATATGGTAGAAGTAGATAAGCTGTATATTTTGTCTTTA
AAGGATCATTATGGGTGA
ATGGGAATCCATTTTACAGAGGATGCCTGGGAAGACTATCTTTATTGGCAAGGTCAGGATAAGAAAACACTCAAGCGAAT
CAATAAGATTATCAAGGATATGCAACGACATCCTTTTGAAGGCATTGCCAAACCAGAACCCTTGAAGTATGATTATCAGG
GTGCCTGGTCTCGGAGAATTGATGCCGAAAATCGGCTGATTTATATGGTAGAAGTAGATAAGCTGTATATTTTGTCTTTA
AAGGATCATTATGGGTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 11082.40 Da Isoelectric Point: 9.2167
>AT214551 WP_005487956.1 NZ_CP082315:c1400895-1400611 [Vibrio alginolyticus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQNAKSR
MEERKARIRNRGKQ
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQNAKSR
MEERKARIRNRGKQ
Download Length: 285 bp
>AT214551 NZ_CP110141:461131-461391 [Streptococcus suis]
ATGGAAGCTATTGTATATTCCCATTTTCGAAATCACTTAAAGGACTATATGAAAAAGGTCAATGACGAGTTTGAACCTTT
GGTCGTGGTTAATAAAAATCCAGAGGAAGATATTGTTGTACTCTCAAAGAGTGAGTGGGATAGTTTACAAGAAACCCTCG
CTGTTGCTCGGAACACTTATCTGTCTCAAAAAGTCCTACGTGGTATGGCTAAAGTCAAAACGGGACAAACCAAAGAACGA
AACCTGATAGAGGCGGACTAA
ATGGAAGCTATTGTATATTCCCATTTTCGAAATCACTTAAAGGACTATATGAAAAAGGTCAATGACGAGTTTGAACCTTT
GGTCGTGGTTAATAAAAATCCAGAGGAAGATATTGTTGTACTCTCAAAGAGTGAGTGGGATAGTTTACAAGAAACCCTCG
CTGTTGCTCGGAACACTTATCTGTCTCAAAAAGTCCTACGTGGTATGGCTAAAGTCAAAACGGGACAAACCAAAGAACGA
AACCTGATAGAGGCGGACTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2I3C6F2 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2I3C6F3 |