Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 11204..11766 Replicon plasmid unnamed1
Accession NZ_CP082312
Organism Vibrio alginolyticus strain HYV1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag K6749_RS23725 Protein ID WP_132937355.1
Coordinates 11204..11506 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag K6749_RS23730 Protein ID WP_039470007.1
Coordinates 11506..11766 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6749_RS23705 (K6749_23595) 6521..7270 - 750 WP_238971032.1 hypothetical protein -
K6749_RS23710 (K6749_23600) 7260..7976 - 717 WP_238971058.1 hypothetical protein -
K6749_RS23715 (K6749_23605) 8925..9993 + 1069 Protein_9 replication initiation protein -
K6749_RS23720 (K6749_23610) 10610..11229 + 620 Protein_10 recombinase family protein -
K6749_RS23725 (K6749_23615) 11204..11506 - 303 WP_132937355.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K6749_RS23730 (K6749_23620) 11506..11766 - 261 WP_039470007.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
K6749_RS23735 (K6749_23625) 11974..12525 + 552 WP_238971060.1 recombinase family protein -
K6749_RS23740 (K6749_23630) 12965..13813 + 849 WP_238971034.1 AHH domain-containing protein -
K6749_RS23745 (K6749_23635) 13928..14617 - 690 WP_222712691.1 hypothetical protein -
K6749_RS23750 (K6749_23640) 15487..16341 + 855 WP_238971036.1 HaeIII family restriction endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..40196 40196


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-57)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11483.27 Da        Isoelectric Point: 9.3611

>T214543 WP_132937355.1 NZ_CP082312:c11506-11204 [Vibrio alginolyticus]
MAQYKLSPAAQTDLVDIRRYTLENWGSAQWTNYFGELKRSMALLANNELIGIDMPELGTGYCRFPLKHHVIYYIKKSDHI
VVAAVLGRNMSPAKHFQQQI

Download         Length: 303 bp

>T214543 NZ_CP110131:2340424-2340678 [Methylorubrum extorquens]
ATGGCTGAGGTCGTCTACAGCAAAGCTGCCTTGAGAGCTTTGACCCGGCTGCCGGCCGACGTGTCTCGGAAGATCCGCCT
CAAGATCGAGCAGTACGCAGCCGAACCCGAGTCGCTCGCCAACAACGTGAAAGCGCTCCGAGGCGAGCCCGGTGTCCTGC
GCCTGCGAGTTGGAGATTGGCGCGTGCTCTTCACCGAGGAAGGCGTCGTGGTTGCGGTTATAAAGATCGCACCACGGGGT
GACGCTTACGACTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9632.96 Da        Isoelectric Point: 4.3449

>AT214543 WP_039470007.1 NZ_CP082312:c11766-11506 [Vibrio alginolyticus]
MQSLTANTAKTKFGDLLMKVQREPVQISKNGSPVAVVMSCEEYEQLEALKMAMVKSRFEQAERDIANGDLVDGETFMNEL
DQGKFD

Download         Length: 261 bp

>AT214543 NZ_CP110131:2340700-2341074 [Methylorubrum extorquens]
ATGAACCCGCAGATCATCATCACCCCCGGCGGCGAGCGTCTCGTGCTGGTGCCTGAGGCAGACTTCGAAGCGCTGGTGGC
AGCGGCCGAAGACAACGCCGACCGCACCGCCGTGGCGGAGTTCAGGCGCAAGCTCGCTGCGGGCGAGGAGGAACTGGTGC
CGGCTTCCGTCGTGGAGCGTCTCGTCTCCGGCGAGAACCGTGTCCGTGTCTGGCGCGAGCACCGTGGCTTGAGTGGAGCC
GCGCTTGCGAAGCAGGCAGGTCTCGCGCAGGCTTACCTGTCGCAGATCGAGACCGGAGCGCGGGAAGGCACAGTGGAAAC
CTACGGCAAGCTTGCCGCGGCTCTCAGCGTTTCCCTGGACGATCTCGCTGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References