Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1310301..1310860 Replicon chromosome
Accession NZ_CP082307
Organism Vibrio alginolyticus strain HNV2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K6748_RS06255 Protein ID WP_238958980.1
Coordinates 1310301..1310579 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K6748_RS06260 Protein ID WP_238958981.1
Coordinates 1310576..1310860 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6748_RS06200 (K6748_06195) 1305989..1306312 - 324 WP_025769024.1 hypothetical protein -
K6748_RS06205 (K6748_06200) 1306441..1306530 + 90 WP_079771093.1 DUF3265 domain-containing protein -
K6748_RS06210 (K6748_06205) 1306634..1306900 + 267 WP_013571723.1 hypothetical protein -
K6748_RS06215 (K6748_06210) 1306937..1307026 + 90 WP_238959013.1 DUF3265 domain-containing protein -
K6748_RS06220 (K6748_06215) 1307172..1307462 + 291 WP_053306455.1 TM2 domain-containing protein -
K6748_RS06225 (K6748_06220) 1307541..1307634 + 94 Protein_1145 DUF3265 domain-containing protein -
K6748_RS06230 (K6748_06225) 1307664..1308029 + 366 WP_238958975.1 VanZ family protein -
K6748_RS06235 (K6748_06230) 1308172..1308642 + 471 WP_238958976.1 GNAT family N-acetyltransferase -
K6748_RS06240 (K6748_06235) 1308766..1309092 + 327 WP_238958977.1 hypothetical protein -
K6748_RS06245 (K6748_06240) 1309784..1310158 + 375 WP_238958978.1 hypothetical protein -
K6748_RS06250 (K6748_06245) 1310180..1310272 + 93 WP_238958979.1 DUF3265 domain-containing protein -
K6748_RS06255 (K6748_06250) 1310301..1310579 - 279 WP_238958980.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K6748_RS06260 (K6748_06255) 1310576..1310860 - 285 WP_238958981.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
K6748_RS06265 (K6748_06260) 1310880..1311029 + 150 WP_238959014.1 DUF3265 domain-containing protein -
K6748_RS06270 (K6748_06265) 1311079..1311510 + 432 WP_042524345.1 DUF1851 domain-containing protein -
K6748_RS06275 (K6748_06270) 1311525..1311617 + 93 WP_196358498.1 DUF3265 domain-containing protein -
K6748_RS06280 (K6748_06275) 1311646..1312287 + 642 WP_238958982.1 hypothetical protein -
K6748_RS06285 (K6748_06280) 1312394..1312864 + 471 WP_205461620.1 GNAT family N-acetyltransferase -
K6748_RS06290 (K6748_06285) 1313006..1313500 + 495 WP_025768998.1 GNAT family N-acetyltransferase -
K6748_RS06295 1313997..1314126 + 130 Protein_1159 DUF3265 domain-containing protein -
K6748_RS06300 1314226..1314537 - 312 Protein_1160 hypothetical protein -
K6748_RS06305 1314693..1314874 + 182 Protein_1161 hypothetical protein -
K6748_RS06310 (K6748_06290) 1315018..1315347 + 330 WP_025769006.1 hypothetical protein -
K6748_RS06315 1315341..1315421 + 81 Protein_1163 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1272150..1350709 78559
- inside Integron - - 1272667..1340786 68119


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(1-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-70)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10920.72 Da        Isoelectric Point: 4.3430

>T214540 WP_238958980.1 NZ_CP082307:c1310579-1310301 [Vibrio alginolyticus]
MILWEEESLNDREKIFEFIYDFNPDAAEKTDNLIEAKVENLLEQPLMGVLRDGVRGRLLIIPEISMIVSYWIEGDIIRIM
RVLHQKQKFPMD

Download         Length: 279 bp

>T214540 NZ_CP110130:c4202680-4202426 [Methylorubrum extorquens]
ATGGCTGAGGTCGTCTACAGCAAAGCTGCCTTGAGAGCTTTGACCCGGCTGCCGGCCGACGTGTCTCGGAAGATCCGCCT
CAAGATCGAGCAGTACGCAGCCGAACCCGAGTCGCTCGCCAACAACGTGAAAGCGCTCCGAGGCGAGCCCGGTGTCCTGC
GCCTGCGAGTTGGAGATTGGCGCGTGCTCTTCACCGAGGAAGGCGTCGTGGTTGCGGTTATAAAGATCGCACCACGGGGT
GACGCTTACGACTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11041.34 Da        Isoelectric Point: 8.0517

>AT214540 WP_238958981.1 NZ_CP082307:c1310860-1310576 [Vibrio alginolyticus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSQ
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT214540 NZ_CP110130:c4202404-4202030 [Methylorubrum extorquens]
ATGAACCCGCAGATCATCATCACCCCCGGCGGCGAGCGTCTCGTGCTGGTGCCTGAGGCAGACTTCGAAGCGCTGGTGGC
AGCGGCCGAAGACAACGCCGACCGCACCGCCGTGGCGGAGTTCAGGCGCAAGCTCGCTGCGGGCGAGGAGGAACTGGTGC
CGGCTTCCGTCGTGGAGCGTCTCGTCTCCGGCGAGAACCGTGTCCGTGTCTGGCGCGAGCACCGTGGCTTGAGTGGAGCC
GCGCTTGCGAAGCAGGCAGGTCTCGCGCAGGCTTACCTGTCGCAGATCGAGACCGGAGCGCGGGAAGGCACAGTGGAAAC
CTACGGCAAGCTTGCCGCGGCTCTCAGCGTTTCCCTGGACGATCTCGCTGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References