Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1835678..1835823 Replicon chromosome
Accession NZ_CP082290
Organism Klebsiella pneumoniae subsp. pneumoniae strain Kp6

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1835714..1835816 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1835678..1835823 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6T93_RS08900 (K6T93_08900) 1830808..1832868 + 2061 WP_004148850.1 oligopeptidase B -
K6T93_RS08905 (K6T93_08905) 1832872..1833531 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6T93_RS08910 (K6T93_08910) 1833610..1833840 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6T93_RS08915 (K6T93_08915) 1833953..1834327 + 375 WP_023285314.1 CopC domain-containing protein YobA -
K6T93_RS08920 (K6T93_08920) 1834331..1835200 + 870 WP_222902713.1 copper homeostasis membrane protein CopD -
K6T93_RS08925 (K6T93_08925) 1835217..1835555 + 339 WP_002911404.1 YebY family protein -
- 1835678..1835823 - 146 - - Antitoxin
- 1835714..1835816 + 103 - - Toxin
K6T93_RS08930 (K6T93_08930) 1836191..1836334 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6T93_RS08935 (K6T93_08935) 1836439..1837407 - 969 WP_004151446.1 VirK/YbjX family protein -
K6T93_RS08940 (K6T93_08940) 1837564..1838217 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
K6T93_RS08945 (K6T93_08945) 1838214..1838405 - 192 WP_002911395.1 YebW family protein -
K6T93_RS08950 (K6T93_08950) 1838503..1838742 - 240 WP_002911393.1 YebV family protein -
K6T93_RS08955 (K6T93_08955) 1838858..1840291 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T214513 NZ_CP082290:1835714-1835816 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT214513 NZ_CP082290:c1835823-1835678 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References