Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 692720..694194 | Replicon | chromosome |
| Accession | NZ_CP082270 | ||
| Organism | Stenotrophomonas sp. DFS-20110405 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | - |
| Locus tag | K5L94_RS03130 | Protein ID | WP_274511991.1 |
| Coordinates | 692720..693595 (-) | Length | 292 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | - |
| Locus tag | K5L94_RS03135 | Protein ID | WP_274511992.1 |
| Coordinates | 693592..694194 (-) | Length | 201 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K5L94_RS03110 (K5L94_03110) | 687768..689153 | - | 1386 | WP_274511990.1 | FAD-linked oxidase C-terminal domain-containing protein | - |
| K5L94_RS03115 (K5L94_03115) | 689587..689955 | - | 369 | WP_187299796.1 | YraN family protein | - |
| K5L94_RS03120 (K5L94_03120) | 689945..691666 | - | 1722 | WP_053451241.1 | penicillin-binding protein activator | - |
| K5L94_RS03125 (K5L94_03125) | 691748..692566 | + | 819 | WP_049458141.1 | 16S rRNA (cytidine(1402)-2'-O)-methyltransferase | - |
| K5L94_RS03130 (K5L94_03130) | 692720..693595 | - | 876 | WP_274511991.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| K5L94_RS03135 (K5L94_03135) | 693592..694194 | - | 603 | WP_274511992.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| K5L94_RS03145 (K5L94_03145) | 694831..695310 | - | 480 | WP_053448795.1 | DM13 domain-containing protein | - |
| K5L94_RS03150 (K5L94_03150) | 695412..696164 | - | 753 | WP_053448796.1 | NRDE family protein | - |
| K5L94_RS03155 (K5L94_03155) | 696533..696934 | + | 402 | WP_008266948.1 | division/cell wall cluster transcriptional repressor MraZ | - |
| K5L94_RS03160 (K5L94_03160) | 696949..697917 | + | 969 | WP_004154215.1 | 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH | - |
| K5L94_RS03165 (K5L94_03165) | 697914..698177 | + | 264 | WP_005412242.1 | cell division protein FtsL | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 292 a.a. Molecular weight: 32599.41 Da Isoelectric Point: 6.4986
>T214481 WP_274511991.1 NZ_CP082270:c693595-692720 [Stenotrophomonas sp. DFS-20110405]
VTPSSLLPLPHRVASIRQRLLDHARARGDDFQFVLDRFAVERLLYRLSTSTFRDQFLLKGAMLFAAWFDAPHRPTRDADF
LGFGSAEPRHLLHITRSLCAMPGNDGLRFDPESITLDATREEAAYEGLRMRLVAYLGRARCHVQWDVGFGDAVIPPPPEI
IYPVMLDELPAPCLRVYPRETVFAEKLEAIAALGIANSRMKDFFDLLALVREDAMDRASLGAAIEATFDRRGTPAPPPPP
YGLSQAFAADTQKQAQWRAFLRRNRLPAPDLSTVLTEIADYLDTLDTAVKP
VTPSSLLPLPHRVASIRQRLLDHARARGDDFQFVLDRFAVERLLYRLSTSTFRDQFLLKGAMLFAAWFDAPHRPTRDADF
LGFGSAEPRHLLHITRSLCAMPGNDGLRFDPESITLDATREEAAYEGLRMRLVAYLGRARCHVQWDVGFGDAVIPPPPEI
IYPVMLDELPAPCLRVYPRETVFAEKLEAIAALGIANSRMKDFFDLLALVREDAMDRASLGAAIEATFDRRGTPAPPPPP
YGLSQAFAADTQKQAQWRAFLRRNRLPAPDLSTVLTEIADYLDTLDTAVKP
Download Length: 876 bp
>T214481 NZ_CP110108:c1380551-1380246 [Alcaligenes sp. SMD-FA]
ATGAACACGATCAACCGCAGCGAAACCTTCAGCACCTGGCTGATAGGCTTAAAAGACCTCAAAGCCAGAGCGAAGATCGT
GGTTCGCATCAAACAAGCCAGCCTGGGCAATTTCGGAGACGTAAAGCCAATTAGTGATGGTGTGTATGAAATGCGCATCC
ACTTCGGTCCTGGCTACCGTCTCTACTATGCTCGTGAGGGCCGTGTGGTCTATCTGCTGCTTAGCGGTGGTGACAAGTCC
TCCCAAAAGCAAGACATCAAAACTGCAATCGCCATGTGGAAACAAATTCAGGAGGATCAATCATGA
ATGAACACGATCAACCGCAGCGAAACCTTCAGCACCTGGCTGATAGGCTTAAAAGACCTCAAAGCCAGAGCGAAGATCGT
GGTTCGCATCAAACAAGCCAGCCTGGGCAATTTCGGAGACGTAAAGCCAATTAGTGATGGTGTGTATGAAATGCGCATCC
ACTTCGGTCCTGGCTACCGTCTCTACTATGCTCGTGAGGGCCGTGTGGTCTATCTGCTGCTTAGCGGTGGTGACAAGTCC
TCCCAAAAGCAAGACATCAAAACTGCAATCGCCATGTGGAAACAAATTCAGGAGGATCAATCATGA
Antitoxin
Download Length: 201 a.a. Molecular weight: 22050.87 Da Isoelectric Point: 11.5774
>AT214481 WP_274511992.1 NZ_CP082270:c694194-693592 [Stenotrophomonas sp. DFS-20110405]
MTDVEAKARKLLRRAGSLRARELVAAGIARVQLSRLVEAGALIRLSRGVYALPGSNNGEADEGLRIIAERMPKVRLCLLS
ALRLHGLTTQAPFELWVAIGNSDRPPRIDWPPLRVVRMSATTLQAGLEERRVGARRVYVSNVAKTVADCFKFRNLVGLDV
AIEALRDALGNRATTPDALMKYARLSRVARLMRPYIDALA
MTDVEAKARKLLRRAGSLRARELVAAGIARVQLSRLVEAGALIRLSRGVYALPGSNNGEADEGLRIIAERMPKVRLCLLS
ALRLHGLTTQAPFELWVAIGNSDRPPRIDWPPLRVVRMSATTLQAGLEERRVGARRVYVSNVAKTVADCFKFRNLVGLDV
AIEALRDALGNRATTPDALMKYARLSRVARLMRPYIDALA
Download Length: 603 bp
>AT214481 NZ_CP110108:c1380249-1379944 [Alcaligenes sp. SMD-FA]
ATGACCACCATTAAAACCGCCCCCTTCGACGCTGCTGAATACCTTGATAGCGAGGAAGCTATTGCCGAGTACCTCTCGGC
TGCTTTGGAAGAAGACGATCCAGCCTTGTTCCTCTCTGCGCTTGCGGATGTGGTCAAAGCCCGAGGCATGACAAAAATGG
CTAAAGACGCCGGTGTAGGCCGAGAAAGCCTGTACAAGGCTCTTGCTCCGGGCGCCAAGCCACGATATGACACTGTCTTG
AAGTTAGCGCGGGCTGCTGGGGTGAAATTAACGGTAGAGCCGATCTCACGTTGTAACGCAACCTAA
ATGACCACCATTAAAACCGCCCCCTTCGACGCTGCTGAATACCTTGATAGCGAGGAAGCTATTGCCGAGTACCTCTCGGC
TGCTTTGGAAGAAGACGATCCAGCCTTGTTCCTCTCTGCGCTTGCGGATGTGGTCAAAGCCCGAGGCATGACAAAAATGG
CTAAAGACGCCGGTGTAGGCCGAGAAAGCCTGTACAAGGCTCTTGCTCCGGGCGCCAAGCCACGATATGACACTGTCTTG
AAGTTAGCGCGGGCTGCTGGGGTGAAATTAACGGTAGAGCCGATCTCACGTTGTAACGCAACCTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|