Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | spoIISABC/SpoIISA-SpoIISB |
| Location | 1272409..1273326 | Replicon | chromosome |
| Accession | NZ_CP082243 | ||
| Organism | Bacillus amyloliquefaciens strain JP3042 | ||
Toxin (Protein)
| Gene name | spoIISA | Uniprot ID | - |
| Locus tag | BAJP3042_RS06510 | Protein ID | WP_032866111.1 |
| Coordinates | 1272580..1273326 (-) | Length | 249 a.a. |
Antitoxin (Protein)
| Gene name | spoIISB | Uniprot ID | I2HQ14 |
| Locus tag | BAJP3042_RS06505 | Protein ID | WP_003154807.1 |
| Coordinates | 1272409..1272579 (-) | Length | 57 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BAJP3042_RS06470 (BAJP3042_06470) | 1267633..1269264 | + | 1632 | WP_222835890.1 | hypothetical protein | - |
| BAJP3042_RS06475 (BAJP3042_06475) | 1269277..1269648 | + | 372 | WP_043021266.1 | XkdW family protein | - |
| BAJP3042_RS06480 (BAJP3042_06480) | 1269653..1269850 | + | 198 | WP_059367156.1 | XkdX family protein | - |
| BAJP3042_RS06485 (BAJP3042_06485) | 1269907..1270668 | + | 762 | WP_043021265.1 | hypothetical protein | - |
| BAJP3042_RS06490 (BAJP3042_06490) | 1270720..1270983 | + | 264 | WP_003154815.1 | hemolysin XhlA family protein | - |
| BAJP3042_RS06495 (BAJP3042_06495) | 1270997..1271260 | + | 264 | WP_003154813.1 | phage holin | - |
| BAJP3042_RS06500 (BAJP3042_06500) | 1271274..1272152 | + | 879 | WP_043021264.1 | N-acetylmuramoyl-L-alanine amidase | - |
| BAJP3042_RS19910 | 1272187..1272312 | - | 126 | WP_023356844.1 | hypothetical protein | - |
| BAJP3042_RS06505 (BAJP3042_06505) | 1272409..1272579 | - | 171 | WP_003154807.1 | type II toxin-antitoxin system SpoIISB family antitoxin | Antitoxin |
| BAJP3042_RS06510 (BAJP3042_06510) | 1272580..1273326 | - | 747 | WP_032866111.1 | type II toxin-antitoxin system SpoIISA family toxin | Toxin |
| BAJP3042_RS06515 (BAJP3042_06515) | 1273430..1274428 | - | 999 | WP_007407255.1 | inorganic phosphate transporter | - |
| BAJP3042_RS06520 (BAJP3042_06520) | 1274441..1275058 | - | 618 | WP_003154804.1 | DUF47 domain-containing protein | - |
| BAJP3042_RS06525 (BAJP3042_06525) | 1275344..1276660 | - | 1317 | WP_222835891.1 | amino acid permease | - |
| BAJP3042_RS06530 (BAJP3042_06530) | 1276983..1277933 | + | 951 | WP_222835892.1 | ring-cleaving dioxygenase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 29095.60 Da Isoelectric Point: 4.7755
>T214452 WP_032866111.1 NZ_CP082243:c1273326-1272580 [Bacillus amyloliquefaciens]
MLMFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG
MLMFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG
Download Length: 747 bp
>T214452 NZ_CP110080:1583896-1584249 [Buttiauxella sp. WJP83]
ATGGCGTGGACCGTAATCTATACCGATGATTTTTATTGTTGGTATAACGAGCAGCCGTTGGACCTGCGTAAACGCATTGT
GGCGATGACGCTCAACATATCAGTGTGGGGGCCTCAACTGGGGCGTCCGTTAGCCGATACGGTGAAAGGTTCGCGCTTTA
CTAACATGAAAGAATTGAGAGTTCAGTGGTGTGGAAAACCTTATCGCTTGTTTTTTGCTTTTGATCCGCTTCAGCGTGCC
GTCGTGTTATGCGGTGGCGATAAAACGGGACGTAAACGCTTTTACGGCGATCTGATAAGGCTCGCAGACACACAGTTTTC
TCGGTATCTGGATGAAATGGAGAGGGATGAATGA
ATGGCGTGGACCGTAATCTATACCGATGATTTTTATTGTTGGTATAACGAGCAGCCGTTGGACCTGCGTAAACGCATTGT
GGCGATGACGCTCAACATATCAGTGTGGGGGCCTCAACTGGGGCGTCCGTTAGCCGATACGGTGAAAGGTTCGCGCTTTA
CTAACATGAAAGAATTGAGAGTTCAGTGGTGTGGAAAACCTTATCGCTTGTTTTTTGCTTTTGATCCGCTTCAGCGTGCC
GTCGTGTTATGCGGTGGCGATAAAACGGGACGTAAACGCTTTTACGGCGATCTGATAAGGCTCGCAGACACACAGTTTTC
TCGGTATCTGGATGAAATGGAGAGGGATGAATGA
Antitoxin
Download Length: 57 a.a. Molecular weight: 6676.74 Da Isoelectric Point: 10.9273
>AT214452 WP_003154807.1 NZ_CP082243:c1272579-1272409 [Bacillus amyloliquefaciens]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA
Download Length: 171 bp
>AT214452 NZ_CP110080:1584246-1584542 [Buttiauxella sp. WJP83]
ATGAAAAAGCTACAAGACGTTATGGCTGAGTTTTCGCCTGAAGATCAAAATGATATCTGGCGCATGGCGCAAGAACTGGT
GCTGGAAACGGGTTTGCAACTGATGCGTGAAGAATTGCAATTCTCACAGAAGCAGGTAGCAGAGGTGATGGGCGTTACTC
AGCCCGCAATAGCGGCTATTGAGCAGCGTGGTAATGATTTAAAAGTGCTGACGCTTAAGCGCTATATCGAAGCAATGGGC
GGGAAACTCTCTTTGTTAGTTCAGCTACCGGAAGGTAATAAAGTGTTCCGAATTTAA
ATGAAAAAGCTACAAGACGTTATGGCTGAGTTTTCGCCTGAAGATCAAAATGATATCTGGCGCATGGCGCAAGAACTGGT
GCTGGAAACGGGTTTGCAACTGATGCGTGAAGAATTGCAATTCTCACAGAAGCAGGTAGCAGAGGTGATGGGCGTTACTC
AGCCCGCAATAGCGGCTATTGAGCAGCGTGGTAATGATTTAAAAGTGCTGACGCTTAAGCGCTATATCGAAGCAATGGGC
GGGAAACTCTCTTTGTTAGTTCAGCTACCGGAAGGTAATAAAGTGTTCCGAATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|