Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mazEF/MazF(toxin) |
| Location | 529985..530622 | Replicon | chromosome |
| Accession | NZ_CP082243 | ||
| Organism | Bacillus amyloliquefaciens strain JP3042 | ||
Toxin (Protein)
| Gene name | mazF | Uniprot ID | G4NU33 |
| Locus tag | BAJP3042_RS02530 | Protein ID | WP_003156187.1 |
| Coordinates | 530272..530622 (+) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | mazE | Uniprot ID | I2HMS5 |
| Locus tag | BAJP3042_RS02525 | Protein ID | WP_003156188.1 |
| Coordinates | 529985..530266 (+) | Length | 94 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BAJP3042_RS02505 (BAJP3042_02505) | 526350..526949 | - | 600 | WP_003156193.1 | rhomboid family intramembrane serine protease | - |
| BAJP3042_RS02510 (BAJP3042_02510) | 527042..527407 | + | 366 | WP_222835674.1 | holo-ACP synthase | - |
| BAJP3042_RS02515 (BAJP3042_02515) | 527572..528579 | + | 1008 | WP_151295737.1 | outer membrane lipoprotein carrier protein LolA | - |
| BAJP3042_RS02520 (BAJP3042_02520) | 528696..529865 | + | 1170 | WP_059368289.1 | alanine racemase | - |
| BAJP3042_RS02525 (BAJP3042_02525) | 529985..530266 | + | 282 | WP_003156188.1 | type II toxin-antitoxin system antitoxin EndoAI | Antitoxin |
| BAJP3042_RS02530 (BAJP3042_02530) | 530272..530622 | + | 351 | WP_003156187.1 | type II toxin-antitoxin system endoribonuclease NdoA | Toxin |
| BAJP3042_RS02535 (BAJP3042_02535) | 530740..531561 | + | 822 | WP_003156182.1 | STAS domain-containing protein | - |
| BAJP3042_RS02540 (BAJP3042_02540) | 531566..531931 | + | 366 | WP_007609584.1 | RsbT antagonist protein RsbS | - |
| BAJP3042_RS02545 (BAJP3042_02545) | 531934..532335 | + | 402 | WP_003156178.1 | anti-sigma regulatory factor | - |
| BAJP3042_RS02550 (BAJP3042_02550) | 532347..533354 | + | 1008 | WP_007410233.1 | PP2C family protein-serine/threonine phosphatase | - |
| BAJP3042_RS02555 (BAJP3042_02555) | 533418..533747 | + | 330 | WP_003156176.1 | anti-sigma factor antagonist RsbV | - |
| BAJP3042_RS02560 (BAJP3042_02560) | 533744..534226 | + | 483 | WP_007609591.1 | anti-sigma B factor RsbW | - |
| BAJP3042_RS02565 (BAJP3042_02565) | 534192..534980 | + | 789 | WP_003156171.1 | RNA polymerase sigma factor SigB | - |
| BAJP3042_RS02570 (BAJP3042_02570) | 534980..535582 | + | 603 | WP_007410234.1 | PP2C family serine/threonine-protein phosphatase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12977.98 Da Isoelectric Point: 4.8781
>T214451 WP_003156187.1 NZ_CP082243:530272-530622 [Bacillus amyloliquefaciens]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMDKVDEALQISLALIDF
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMDKVDEALQISLALIDF
Download Length: 351 bp
>T214451 NZ_CP110080:776597-777019 [Buttiauxella sp. WJP83]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCCTGGCGTGCGCAATGGATATCTCTTTTGGTCCACGGGATGATTGCACT
GTTTGTGCTTTTAATGCCGTGGCCGATGAGCTACACGCTAATTTGGATGCTGCTGCTTTCGTTGGTGGTCTTTGACAGCG
TGCGCAGCCAGCGCCGTATTCATGCTTGCCAGGGCGAAATGAAACTTCTGACCGATTACCACCTGCGGTGGCAAAACCAG
GAGTGGGAGATTGTCGGTGCGCCTTGGGTCTTACGCAGTGGCATGATGCTGCGTTTACGCCGTCTTGGACGTAAACGCTG
CCAACATCTATGGCTGTCTGCCGACAGTATGGATATTGGCGAATGGCGAGATTTACGCCGCCTGATGCAGCAACAACAGG
CAAGCGGGAGTGGGGAAGTTTAA
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCCTGGCGTGCGCAATGGATATCTCTTTTGGTCCACGGGATGATTGCACT
GTTTGTGCTTTTAATGCCGTGGCCGATGAGCTACACGCTAATTTGGATGCTGCTGCTTTCGTTGGTGGTCTTTGACAGCG
TGCGCAGCCAGCGCCGTATTCATGCTTGCCAGGGCGAAATGAAACTTCTGACCGATTACCACCTGCGGTGGCAAAACCAG
GAGTGGGAGATTGTCGGTGCGCCTTGGGTCTTACGCAGTGGCATGATGCTGCGTTTACGCCGTCTTGGACGTAAACGCTG
CCAACATCTATGGCTGTCTGCCGACAGTATGGATATTGGCGAATGGCGAGATTTACGCCGCCTGATGCAGCAACAACAGG
CAAGCGGGAGTGGGGAAGTTTAA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10562.92 Da Isoelectric Point: 6.4706
>AT214451 WP_003156188.1 NZ_CP082243:529985-530266 [Bacillus amyloliquefaciens]
MSESSARTEMKISLPENLVAELDGVAMREKRSRNELISQAVRAYVSERTTRHNRDLMRRGYMEMAKINLNISSEAHYAEC
EAETTVERLVSGG
MSESSARTEMKISLPENLVAELDGVAMREKRSRNELISQAVRAYVSERTTRHNRDLMRRGYMEMAKINLNISSEAHYAEC
EAETTVERLVSGG
Download Length: 282 bp
>AT214451 NZ_CP110080:776350-776616 [Buttiauxella sp. WJP83]
ATGGATATCAATAATAAAGCCCGAATTCATTGGGCGTGCCGTCGGGGAATGCGTGAGCTTGATATTTCGATTATGCCATT
CTTCGAATATGAATATGACTCGTTAAGCACTGAGGATAAGCAGTTGTTTGTCCGCTTGCTGGAAAGCGATGATCCTGACC
TGTTTAACTGGTTAATGAATCATGGCAAACCGGCAGATACAGAGCTGCAGCGGATGGTGACACTGATTCAGACACGGAAT
AAAGAACGTGGTCCTGTGGCAATCTGA
ATGGATATCAATAATAAAGCCCGAATTCATTGGGCGTGCCGTCGGGGAATGCGTGAGCTTGATATTTCGATTATGCCATT
CTTCGAATATGAATATGACTCGTTAAGCACTGAGGATAAGCAGTTGTTTGTCCGCTTGCTGGAAAGCGATGATCCTGACC
TGTTTAACTGGTTAATGAATCATGGCAAACCGGCAGATACAGAGCTGCAGCGGATGGTGACACTGATTCAGACACGGAAT
AAAGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|