Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-dnstrm_HI1420
Location 174604..175223 Replicon chromosome
Accession NZ_CP082238
Organism Acidithiobacillus ferrooxidans strain BYM

Toxin (Protein)


Gene name PumA Uniprot ID A0A2W1KCH5
Locus tag K7B00_RS00850 Protein ID WP_031575563.1
Coordinates 174927..175223 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K7B00_RS00845 Protein ID WP_031575560.1
Coordinates 174604..174921 (-) Length 106 a.a.

Genomic Context

K7B00_RS16605K7B00_RS00825K7B00_RS00830K7B00_RS00835K7B00_RS00840K7B00_RS00855K7B00_RS00865K7B00_RS00870K7B00_RS00875K7B00_RS00845K7B00_RS00850K7B00_RS00860
Location: 170134..171279 (1146 bp)
Type: Others
Protein ID: WP_229129756.1
Location: 171361..172101 (741 bp)
Type: Others
Protein ID: WP_054608922.1
Location: 172113..172367 (255 bp)
Type: Others
Protein ID: WP_012535920.1
Location: 172381..174075 (1695 bp)
Type: Others
Protein ID: WP_054608923.1
Location: 174146..174550 (405 bp)
Type: Others
Protein ID: WP_031575557.1
Location: 175444..175848 (405 bp)
Type: Others
Protein ID: WP_031575566.1
Location: 176911..177579 (669 bp)
Type: Others
Protein ID: WP_054608924.1
Location: 177592..178692 (1101 bp)
Type: Others
Protein ID: WP_054608925.1
Location: 178694..179698 (1005 bp)
Type: Others
Protein ID: WP_054608926.1
Location: 174604..174921 (318 bp)
Type: Antitoxin
Protein ID: WP_031575560.1
Location: 174927..175223 (297 bp)
Type: Toxin
Protein ID: WP_031575563.1
Location: 175841..176761 (921 bp)
Type: Others
Protein ID: WP_146235851.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
K7B00_RS16605170134..171279+1146WP_229129756.1hypothetical protein-
K7B00_RS00825 (K7B00_00825)171361..172101+741WP_054608922.1P-type conjugative transfer protein TrbJ-
K7B00_RS00830 (K7B00_00830)172113..172367+255WP_012535920.1EexN family lipoprotein-
K7B00_RS00835 (K7B00_00835)172381..174075+1695WP_054608923.1P-type conjugative transfer protein TrbL-
K7B00_RS00840 (K7B00_00840)174146..174550+405WP_031575557.1hypothetical protein-
K7B00_RS00845 (K7B00_00845)174604..174921-318WP_031575560.1putative addiction module antidote proteinAntitoxin
K7B00_RS00850 (K7B00_00850)174927..175223-297WP_031575563.1type II toxin-antitoxin system RelE/ParE family toxinToxin
K7B00_RS00855 (K7B00_00855)175444..175848+405WP_031575566.1hypothetical protein-
K7B00_RS00860 (K7B00_00860)175841..176761-921WP_146235851.1hypothetical protein-
K7B00_RS00865 (K7B00_00865)176911..177579+669WP_054608924.1type IV secretion system protein-
K7B00_RS00870 (K7B00_00870)177592..178692+1101WP_054608925.1TrbG/VirB9 family P-type conjugative transfer protein-
K7B00_RS00875 (K7B00_00875)178694..179698+1005WP_054608926.1TrbG/VirB9 family P-type conjugative transfer protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Uncharacterized protein HI1420

(4-94)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11112.88 Da        Isoelectric Point: 9.6531

>T214438 WP_031575563.1 NZ_CP082238:c175223-174927 [Acidithiobacillus ferrooxidans]
MLELIETNVFREWLEGLRDHQARARIQVRMRRLSLGNPGDVKPVGEGISEMRIDYGPGYRVYFMRRGPVVVALLCGGDKG
SQERDIALAKAIAAQWKE

Download         Length: 297 bp

>T214438 NZ_CP110074:c2644701-2644600 [Enterococcus faecalis]
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCACTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACAATAAAAAATAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11253.69 Da        Isoelectric Point: 6.2117

>AT214438 WP_031575560.1 NZ_CP082238:c174921-174604 [Acidithiobacillus ferrooxidans]
MEVQFRRYDTVNYLKTEDDIAHYLDAAMEDGDPALILAALGDVARARNLSQLARDAGMSRQGLDKALSGTGNPSLVTVLK
ITQALGLRLSFQPAHTSSHPSATGV

Download         Length: 318 bp

>AT214438 NZ_CP110074:2644481-2644655 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTT
TTGAATCTTAACCGTTCGGCCTACGAAGCTTGTGAACGGTTATTTTTTATTGTTTTTCGTTGCTTCAAGGATACCGAAAA
TCAGTAGTGCAACAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A2W1KCH5

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References