Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE(toxin) |
Location | 5625577..5626057 | Replicon | chromosome |
Accession | NZ_CP082236 | ||
Organism | Pseudomonas sp. SC3(2021) |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | K5Y35_RS24965 | Protein ID | WP_222833239.1 |
Coordinates | 5625764..5626057 (+) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | K5Y35_RS24960 | Protein ID | WP_159815041.1 |
Coordinates | 5625577..5625783 (+) | Length | 69 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
K5Y35_RS24945 | 5621021..5623249 | + | 2229 | WP_222833236.1 | Ig-like domain-containing protein | - |
K5Y35_RS24950 | 5623322..5623786 | + | 465 | WP_222833237.1 | curlin | - |
K5Y35_RS24955 | 5623815..5625266 | + | 1452 | WP_222833238.1 | curlin | - |
K5Y35_RS24960 | 5625577..5625783 | + | 207 | WP_159815041.1 | antitoxin | Antitoxin |
K5Y35_RS24965 | 5625764..5626057 | + | 294 | WP_222833239.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
K5Y35_RS24970 | 5626202..5626630 | + | 429 | WP_222833240.1 | hypothetical protein | - |
K5Y35_RS24975 | 5626680..5626928 | - | 249 | WP_222833241.1 | antitoxin | - |
K5Y35_RS24980 | 5627080..5627451 | - | 372 | WP_186747846.1 | DUF6124 family protein | - |
K5Y35_RS24985 | 5628738..5629598 | - | 861 | WP_222833242.1 | CsgG/HfaB family protein | - |
K5Y35_RS24990 | 5629628..5630059 | - | 432 | WP_128615748.1 | curli assembly protein CsgF | - |
K5Y35_RS24995 | 5630056..5630448 | - | 393 | WP_093439237.1 | curli production assembly/transport protein CsgE | - |
K5Y35_RS25000 | 5630445..5630984 | - | 540 | WP_222833243.1 | type II secretion system GspH family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11313.17 Da Isoelectric Point: 10.0609
>T214434 WP_222833239.1 NZ_CP082236:5625764-5626057 [Pseudomonas sp. SC3(2021)]
MVSRPIEWRPEARAKLVTVLEYIVERNVVAAKEILKAVGKAIAYLPDHPYLYRSGRITGTREIVVNSSYLIIYRVTDRIE
IVNVLHARQEYPRRDSF
MVSRPIEWRPEARAKLVTVLEYIVERNVVAAKEILKAVGKAIAYLPDHPYLYRSGRITGTREIVVNSSYLIIYRVTDRIE
IVNVLHARQEYPRRDSF
Download Length: 294 bp
>T214434 NZ_CP110073:29274-29462 [Enterococcus faecalis]
ATGCCACTTACCGGAAAGCAAATGCTAAAGCTCTTAAAAAATAATGGTTGGATTGAACGAAGACAAGAAGGCTCACATCA
TCACTTATACAAAGATGGCGTAAGAATTACAGTACCAGTTCATGGAAATCAAGATTTAGGAAAAGGGCTAGAGCGAAAAA
TCTTAAAAGATGCAGGGCTAAAAAAATAG
ATGCCACTTACCGGAAAGCAAATGCTAAAGCTCTTAAAAAATAATGGTTGGATTGAACGAAGACAAGAAGGCTCACATCA
TCACTTATACAAAGATGGCGTAAGAATTACAGTACCAGTTCATGGAAATCAAGATTTAGGAAAAGGGCTAGAGCGAAAAA
TCTTAAAAGATGCAGGGCTAAAAAAATAG
Antitoxin
Download Length: 69 a.a. Molecular weight: 7680.59 Da Isoelectric Point: 4.0676
>AT214434 WP_159815041.1 NZ_CP082236:5625577-5625783 [Pseudomonas sp. SC3(2021)]
MIDPKMIDPLCPVVSDLDPEEQAASYDRWFRAEVQASLDDPRPNLSHEQVMAEIHALIKAKDNGFEAD
MIDPKMIDPLCPVVSDLDPEEQAASYDRWFRAEVQASLDDPRPNLSHEQVMAEIHALIKAKDNGFEAD
Download Length: 207 bp
>AT214434 NZ_CP110073:29494-29955 [Enterococcus faecalis]
ATGTCATTACAAACATCTTTGAAAGTCGCTTATCCTGCTATTTTTCATCCAGAAGAGGGTGGGGGATACTTTATTGAATT
TCCAGATGTTCAAGGAGCGTATACAGGTATAAATGAAAATGATATAGCCTATGGTTTATTGATGGCTGAAGAAGTTTTAG
GTATGGTGTTAGCTGATTATATTGAAAATAATGAGACGTTGCCTAAAGCGAGCGAATTAAATAGTATAAGTCATAAACCT
GATGAATTTGTCACTATGGTTTTAGTTGATATAGAAGAATATTTTAAAGACATGAAACCAGTAAAAAAGACGCTAACGAT
CCCAAGTTGGGCTAATAATTGGGGAAATAGAGTAGGGATAAATTTTTCGCAACTGTTAACGGAATCGATCGCACAGACAG
CAATAAATTACACACAAGAGACATTAAAGGAAACAAAAGAAAAATACGAAGTAAAAAATTAA
ATGTCATTACAAACATCTTTGAAAGTCGCTTATCCTGCTATTTTTCATCCAGAAGAGGGTGGGGGATACTTTATTGAATT
TCCAGATGTTCAAGGAGCGTATACAGGTATAAATGAAAATGATATAGCCTATGGTTTATTGATGGCTGAAGAAGTTTTAG
GTATGGTGTTAGCTGATTATATTGAAAATAATGAGACGTTGCCTAAAGCGAGCGAATTAAATAGTATAAGTCATAAACCT
GATGAATTTGTCACTATGGTTTTAGTTGATATAGAAGAATATTTTAAAGACATGAAACCAGTAAAAAAGACGCTAACGAT
CCCAAGTTGGGCTAATAATTGGGGAAATAGAGTAGGGATAAATTTTTCGCAACTGTTAACGGAATCGATCGCACAGACAG
CAATAAATTACACACAAGAGACATTAAAGGAAACAAAAGAAAAATACGAAGTAAAAAATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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