Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 5625577..5626057 Replicon chromosome
Accession NZ_CP082236
Organism Pseudomonas sp. SC3(2021)

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K5Y35_RS24965 Protein ID WP_222833239.1
Coordinates 5625764..5626057 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K5Y35_RS24960 Protein ID WP_159815041.1
Coordinates 5625577..5625783 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5Y35_RS24945 5621021..5623249 + 2229 WP_222833236.1 Ig-like domain-containing protein -
K5Y35_RS24950 5623322..5623786 + 465 WP_222833237.1 curlin -
K5Y35_RS24955 5623815..5625266 + 1452 WP_222833238.1 curlin -
K5Y35_RS24960 5625577..5625783 + 207 WP_159815041.1 antitoxin Antitoxin
K5Y35_RS24965 5625764..5626057 + 294 WP_222833239.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K5Y35_RS24970 5626202..5626630 + 429 WP_222833240.1 hypothetical protein -
K5Y35_RS24975 5626680..5626928 - 249 WP_222833241.1 antitoxin -
K5Y35_RS24980 5627080..5627451 - 372 WP_186747846.1 DUF6124 family protein -
K5Y35_RS24985 5628738..5629598 - 861 WP_222833242.1 CsgG/HfaB family protein -
K5Y35_RS24990 5629628..5630059 - 432 WP_128615748.1 curli assembly protein CsgF -
K5Y35_RS24995 5630056..5630448 - 393 WP_093439237.1 curli production assembly/transport protein CsgE -
K5Y35_RS25000 5630445..5630984 - 540 WP_222833243.1 type II secretion system GspH family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11313.17 Da        Isoelectric Point: 10.0609

>T214434 WP_222833239.1 NZ_CP082236:5625764-5626057 [Pseudomonas sp. SC3(2021)]
MVSRPIEWRPEARAKLVTVLEYIVERNVVAAKEILKAVGKAIAYLPDHPYLYRSGRITGTREIVVNSSYLIIYRVTDRIE
IVNVLHARQEYPRRDSF

Download         Length: 294 bp

>T214434 NZ_CP110073:29274-29462 [Enterococcus faecalis]
ATGCCACTTACCGGAAAGCAAATGCTAAAGCTCTTAAAAAATAATGGTTGGATTGAACGAAGACAAGAAGGCTCACATCA
TCACTTATACAAAGATGGCGTAAGAATTACAGTACCAGTTCATGGAAATCAAGATTTAGGAAAAGGGCTAGAGCGAAAAA
TCTTAAAAGATGCAGGGCTAAAAAAATAG

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7680.59 Da        Isoelectric Point: 4.0676

>AT214434 WP_159815041.1 NZ_CP082236:5625577-5625783 [Pseudomonas sp. SC3(2021)]
MIDPKMIDPLCPVVSDLDPEEQAASYDRWFRAEVQASLDDPRPNLSHEQVMAEIHALIKAKDNGFEAD

Download         Length: 207 bp

>AT214434 NZ_CP110073:29494-29955 [Enterococcus faecalis]
ATGTCATTACAAACATCTTTGAAAGTCGCTTATCCTGCTATTTTTCATCCAGAAGAGGGTGGGGGATACTTTATTGAATT
TCCAGATGTTCAAGGAGCGTATACAGGTATAAATGAAAATGATATAGCCTATGGTTTATTGATGGCTGAAGAAGTTTTAG
GTATGGTGTTAGCTGATTATATTGAAAATAATGAGACGTTGCCTAAAGCGAGCGAATTAAATAGTATAAGTCATAAACCT
GATGAATTTGTCACTATGGTTTTAGTTGATATAGAAGAATATTTTAAAGACATGAAACCAGTAAAAAAGACGCTAACGAT
CCCAAGTTGGGCTAATAATTGGGGAAATAGAGTAGGGATAAATTTTTCGCAACTGTTAACGGAATCGATCGCACAGACAG
CAATAAATTACACACAAGAGACATTAAAGGAAACAAAAGAAAAATACGAAGTAAAAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References