214385

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 865348..867068 Replicon chromosome
Accession NZ_CP082217
Organism Xanthomonas cucurbitae strain KS_456

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag K6980_RS03570 Protein ID WP_104602389.1
Coordinates 866418..867068 (-) Length 217 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag K6980_RS03565 Protein ID WP_104602390.1
Coordinates 865348..866418 (-) Length 357 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6980_RS03545 (K6980_03530) 860907..861723 + 817 Protein_704 cellulase -
K6980_RS03550 (K6980_03535) 861869..863149 - 1281 WP_104602393.1 amidohydrolase family protein -
K6980_RS03555 (K6980_03540) 863146..864546 - 1401 WP_104602392.1 amidohydrolase -
K6980_RS03560 (K6980_03545) 864686..865246 + 561 WP_104602391.1 DUF924 family protein -
K6980_RS03565 (K6980_03550) 865348..866418 - 1071 WP_104602390.1 macro domain-containing protein Antitoxin
K6980_RS03570 (K6980_03555) 866418..867068 - 651 WP_104602389.1 DUF4433 domain-containing protein Toxin
K6980_RS03575 (K6980_03560) 867318..868244 - 927 WP_104602388.1 Grx4 family monothiol glutaredoxin -
K6980_RS03580 (K6980_03565) 868290..869081 + 792 WP_208800396.1 polysaccharide deacetylase family protein -
K6980_RS03585 (K6980_03570) 869281..869952 - 672 WP_104602386.1 methyltransferase -
K6980_RS03590 (K6980_03575) 870093..870494 - 402 WP_146090297.1 hypothetical protein -
K6980_RS03595 (K6980_03580) 870501..871151 - 651 WP_104602384.1 SGNH/GDSL hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(16-216)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 217 a.a.        Molecular weight: 25041.42 Da        Isoelectric Point: 7.2475

>T214385 WP_104602389.1 NZ_CP082217:c867068-866418 [Xanthomonas cucurbitae]
MSRRYLNLNPDKALIWRIVHRDNLPWILDNGLHCGNGSARSPGWVSIGNPELIDKRACHPVPLTPGGFLNDYVPFYFTPF
SPMLRNIQTGWGGIQQRANDEIVILVSSLHHVKARGWPFLFTDSHAYYQLTTFHSDLTNLDTIDWSLIQARDFRRDQEDP
AKFERYQAEALVHRHLPVDGLLGIVCYTDDMKRSIERQLEARNLALSVHARTEWYF

Download         Length: 651 bp

>T214385 NZ_CP110059:2759782-2759925 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTAAAAGAAAACAATAAAAAATAA

Antitoxin


Download         Length: 357 a.a.        Molecular weight: 39867.77 Da        Isoelectric Point: 6.2605

>AT214385 WP_104602390.1 NZ_CP082217:c866418-865348 [Xanthomonas cucurbitae]
MITFTQGNLLQARVEALVNTVNTVGVMGKGIALMFKERFNENFLRYAAACKAKEVQIGKMFVTATSELDGPRWIINFPTK
QHWRGDSRIEWITDGLQDLRLFLIENKVESIAIPPLGAGNGGLDWADVRPLIEEALAGLDTNILVFEPTPRYQNVAKRSG
VEKLTPARALIAELVRRYWVLGVECSLLEIQKLAWFLERNIERAGLPTLDLRFAPHRYGPYTDRLRHLLDGLDGSYLHCD
KRIGDADPLDVIWFDDSRKSFVQSYLKSEAKQYAPALEATAALIDGFESPFGMELLATIDWLVVREGISPQVADIREGIR
HWPGGPDAAARKDRLFNDRALGIALERLTSHAAAAS

Download         Length: 1071 bp

>AT214385 NZ_CP110059:c2760119-2759857 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGACAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTTTTCTTTTACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References