214377

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3705307..3707030 Replicon chromosome
Accession NZ_CP082214
Organism Xanthomonas cucurbitae strain OH_261

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag K6978_RS16315 Protein ID WP_274396541.1
Coordinates 3705307..3705960 (+) Length 218 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag K6978_RS16320 Protein ID WP_104602390.1
Coordinates 3705960..3707030 (+) Length 357 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6978_RS16290 (K6978_16220) 3701224..3701874 + 651 WP_274396540.1 SGNH/GDSL hydrolase family protein -
K6978_RS16295 (K6978_16225) 3701881..3702282 + 402 WP_159407551.1 hypothetical protein -
K6978_RS16300 (K6978_16230) 3702423..3703094 + 672 WP_104602386.1 methyltransferase -
K6978_RS16305 (K6978_16235) 3703294..3704085 - 792 WP_208800396.1 polysaccharide deacetylase family protein -
K6978_RS16310 (K6978_16240) 3704131..3705057 + 927 WP_104602388.1 Grx4 family monothiol glutaredoxin -
K6978_RS16315 (K6978_16245) 3705307..3705960 + 654 WP_274396541.1 DUF4433 domain-containing protein Toxin
K6978_RS16320 (K6978_16250) 3705960..3707030 + 1071 WP_104602390.1 macro domain-containing protein Antitoxin
K6978_RS16325 (K6978_16255) 3707132..3707692 - 561 WP_104602391.1 DUF924 family protein -
K6978_RS16330 (K6978_16260) 3707832..3709232 + 1401 WP_274396542.1 amidohydrolase -
K6978_RS16335 (K6978_16265) 3709229..3710509 + 1281 WP_274396543.1 amidohydrolase family protein -
K6978_RS16340 (K6978_16270) 3710656..3711471 - 816 WP_274396544.1 cellulase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(16-217)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 218 a.a.        Molecular weight: 25156.51 Da        Isoelectric Point: 7.0179

>T214377 WP_274396541.1 NZ_CP082214:3705307-3705960 [Xanthomonas cucurbitae]
MSRRYLNLNPDKALIWRIVHRDNLPWILDNGLHCGNGSARSPGWVSIGNPELIDKRACHPVPLTPGGFLNDYVPFYFTPF
SPMLRNIQTGWGGIQQRANDEIVILVSSLHHVKARGWPFLFTDSHAYYQLTTFHSDLTNLDTIDWSLIQARDFRRDQEDP
AKFERYQAEALVHRHLPVDGLLGIVCYTDDMKRSIERQLEARNLALSVHARTDEWYF

Download         Length: 654 bp

>T214377 NZ_CP110059:514084-514200 [Enterococcus faecalis]
ATGTTTTTGTCCGTTGAAGCAGCGCTAGGACTGATGATTAGTTTTGCAATACTTGTTGTGACCATTATCTTCGGTATCTT
AGCGCTTGTCTTAGACAACAAAAATAACCGTTCATAA

Antitoxin


Download         Length: 357 a.a.        Molecular weight: 39867.77 Da        Isoelectric Point: 6.2605

>AT214377 WP_104602390.1 NZ_CP082214:3705960-3707030 [Xanthomonas cucurbitae]
MITFTQGNLLQARVEALVNTVNTVGVMGKGIALMFKERFNENFLRYAAACKAKEVQIGKMFVTATSELDGPRWIINFPTK
QHWRGDSRIEWITDGLQDLRLFLIENKVESIAIPPLGAGNGGLDWADVRPLIEEALAGLDTNILVFEPTPRYQNVAKRSG
VEKLTPARALIAELVRRYWVLGVECSLLEIQKLAWFLERNIERAGLPTLDLRFAPHRYGPYTDRLRHLLDGLDGSYLHCD
KRIGDADPLDVIWFDDSRKSFVQSYLKSEAKQYAPALEATAALIDGFESPFGMELLATIDWLVVREGISPQVADIREGIR
HWPGGPDAAARKDRLFNDRALGIALERLTSHAAAAS

Download         Length: 1071 bp

>AT214377 NZ_CP110059:c514316-514111 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTATTGCAAAACTAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References