214372

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3708033..3709756 Replicon chromosome
Accession NZ_CP082213
Organism Xanthomonas cucurbitae strain WI_206

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag K6981_RS16330 Protein ID WP_274396541.1
Coordinates 3708033..3708686 (+) Length 218 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag K6981_RS16335 Protein ID WP_104602390.1
Coordinates 3708686..3709756 (+) Length 357 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6981_RS16305 (K6981_16250) 3703950..3704600 + 651 WP_274396540.1 SGNH/GDSL hydrolase family protein -
K6981_RS16310 (K6981_16255) 3704607..3705008 + 402 WP_159407551.1 hypothetical protein -
K6981_RS16315 (K6981_16260) 3705149..3705820 + 672 WP_104602386.1 methyltransferase -
K6981_RS16320 (K6981_16265) 3706020..3706811 - 792 WP_208800396.1 polysaccharide deacetylase family protein -
K6981_RS16325 (K6981_16270) 3706857..3707783 + 927 WP_104602388.1 Grx4 family monothiol glutaredoxin -
K6981_RS16330 (K6981_16275) 3708033..3708686 + 654 WP_274396541.1 DUF4433 domain-containing protein Toxin
K6981_RS16335 (K6981_16280) 3708686..3709756 + 1071 WP_104602390.1 macro domain-containing protein Antitoxin
K6981_RS16340 (K6981_16285) 3709858..3710418 - 561 WP_104602391.1 DUF924 family protein -
K6981_RS16345 (K6981_16290) 3710558..3711958 + 1401 WP_274396542.1 amidohydrolase -
K6981_RS16350 (K6981_16295) 3711955..3713235 + 1281 WP_274396543.1 amidohydrolase family protein -
K6981_RS16355 (K6981_16300) 3713382..3714197 - 816 WP_274396544.1 cellulase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(16-217)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 218 a.a.        Molecular weight: 25156.51 Da        Isoelectric Point: 7.0179

>T214372 WP_274396541.1 NZ_CP082213:3708033-3708686 [Xanthomonas cucurbitae]
MSRRYLNLNPDKALIWRIVHRDNLPWILDNGLHCGNGSARSPGWVSIGNPELIDKRACHPVPLTPGGFLNDYVPFYFTPF
SPMLRNIQTGWGGIQQRANDEIVILVSSLHHVKARGWPFLFTDSHAYYQLTTFHSDLTNLDTIDWSLIQARDFRRDQEDP
AKFERYQAEALVHRHLPVDGLLGIVCYTDDMKRSIERQLEARNLALSVHARTDEWYF

Download         Length: 654 bp

>T214372 NZ_CP110054:2759717-2759860 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTAAAAGAAAACAATAAAAAATAA

Antitoxin


Download         Length: 357 a.a.        Molecular weight: 39867.77 Da        Isoelectric Point: 6.2605

>AT214372 WP_104602390.1 NZ_CP082213:3708686-3709756 [Xanthomonas cucurbitae]
MITFTQGNLLQARVEALVNTVNTVGVMGKGIALMFKERFNENFLRYAAACKAKEVQIGKMFVTATSELDGPRWIINFPTK
QHWRGDSRIEWITDGLQDLRLFLIENKVESIAIPPLGAGNGGLDWADVRPLIEEALAGLDTNILVFEPTPRYQNVAKRSG
VEKLTPARALIAELVRRYWVLGVECSLLEIQKLAWFLERNIERAGLPTLDLRFAPHRYGPYTDRLRHLLDGLDGSYLHCD
KRIGDADPLDVIWFDDSRKSFVQSYLKSEAKQYAPALEATAALIDGFESPFGMELLATIDWLVVREGISPQVADIREGIR
HWPGGPDAAARKDRLFNDRALGIALERLTSHAAAAS

Download         Length: 1071 bp

>AT214372 NZ_CP110054:c2759620-2759419 [Enterococcus faecalis]
GTTTTTTTAGGTGATTGTGCTGTAATAGCAATGAAAAGAGAGATATGCGCCAACATACCTCTCTGATGTAGAGCCGTTTA
AGACGGTGATCTTTTTGATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCA
ATTTCACAATCAGTGCAATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References