Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2079257..2079402 Replicon chromosome
Accession NZ_CP082212
Organism Klebsiella pneumoniae strain BJ20

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2079293..2079395 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2079257..2079402 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6039_RS10335 (K6039_10310) 2074387..2076447 + 2061 WP_004151449.1 oligopeptidase B -
K6039_RS10340 (K6039_10315) 2076451..2077110 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6039_RS10345 (K6039_10320) 2077189..2077419 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6039_RS10350 (K6039_10325) 2077532..2077906 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6039_RS10355 (K6039_10330) 2077910..2078779 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
K6039_RS10360 (K6039_10335) 2078796..2079134 + 339 WP_002911404.1 YebY family protein -
- 2079257..2079402 - 146 - - Antitoxin
- 2079293..2079395 + 103 - - Toxin
K6039_RS10365 (K6039_10340) 2079770..2079913 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6039_RS10370 (K6039_10345) 2080018..2080986 - 969 WP_004151446.1 VirK/YbjX family protein -
K6039_RS10375 (K6039_10350) 2081143..2081796 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K6039_RS10380 (K6039_10355) 2081793..2081984 - 192 WP_002911395.1 YebW family protein -
K6039_RS10385 (K6039_10360) 2082082..2082321 - 240 WP_002911393.1 YebV family protein -
K6039_RS10390 (K6039_10365) 2082437..2083870 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T214355 NZ_CP082212:2079293-2079395 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT214355 NZ_CP082212:c2079402-2079257 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References