Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1990368..1990513 Replicon chromosome
Accession NZ_CP082211
Organism Klebsiella pneumoniae strain A1718

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1990404..1990506 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1990368..1990513 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6036_RS09530 1985498..1987558 + 2061 WP_004151449.1 oligopeptidase B -
K6036_RS09535 1987562..1988221 - 660 WP_020324964.1 exodeoxyribonuclease X -
K6036_RS09540 1988300..1988530 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6036_RS09545 1988643..1989017 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6036_RS09550 1989021..1989890 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
K6036_RS09555 1989907..1990245 + 339 WP_002911404.1 YebY family protein -
- 1990368..1990513 - 146 - - Antitoxin
- 1990404..1990506 + 103 - - Toxin
K6036_RS09560 1990882..1991025 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6036_RS09565 1991130..1992098 - 969 WP_004151446.1 VirK/YbjX family protein -
K6036_RS09570 1992255..1992908 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
K6036_RS09575 1992905..1993096 - 192 WP_002911395.1 YebW family protein -
K6036_RS09580 1993194..1993433 - 240 WP_002911393.1 YebV family protein -
K6036_RS09585 1993549..1994982 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T214335 NZ_CP082211:1990404-1990506 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT214335 NZ_CP082211:c1990513-1990368 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References