Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2047223..2047368 Replicon chromosome
Accession NZ_CP082207
Organism Klebsiella pneumoniae strain KPN43G

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2047259..2047361 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2047223..2047368 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6032_RS09805 2042353..2044413 + 2061 WP_004151449.1 oligopeptidase B -
K6032_RS09810 2044417..2045076 - 660 WP_002911407.1 exodeoxyribonuclease X -
K6032_RS09815 2045155..2045385 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K6032_RS09820 2045498..2045872 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K6032_RS09825 2045876..2046745 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
K6032_RS09830 2046762..2047100 + 339 WP_016529031.1 YebY family protein -
- 2047223..2047368 - 146 - - Antitoxin
- 2047259..2047361 + 103 - - Toxin
K6032_RS09835 2047736..2047879 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K6032_RS09840 2047984..2048952 - 969 WP_004151446.1 VirK/YbjX family protein -
K6032_RS09845 2049109..2049675 + 567 WP_094935968.1 metallophosphoesterase -
K6032_RS09850 2049672..2049863 - 192 WP_002911395.1 YebW family protein -
K6032_RS09855 2049961..2050200 - 240 WP_002911393.1 YebV family protein -
K6032_RS09860 2050316..2051749 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T214313 NZ_CP082207:2047259-2047361 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT214313 NZ_CP082207:c2047368-2047223 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References