Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3421458..3423178 Replicon chromosome
Accession NZ_CP082178
Organism Xanthomonas fragariae strain SHQP01

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag K4A87_RS16395 Protein ID WP_208587619.1
Coordinates 3421458..3422108 (+) Length 217 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag K4A87_RS16400 Protein ID WP_238135557.1
Coordinates 3422147..3423178 (+) Length 344 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K4A87_RS16370 (K4A87_16280) 3416838..3417509 + 672 WP_208587614.1 methyltransferase -
K4A87_RS16375 (K4A87_16285) 3417614..3418960 - 1347 WP_208587615.1 IS701 family transposase -
K4A87_RS16385 (K4A87_16295) 3419375..3420166 - 792 WP_208587616.1 polysaccharide deacetylase family protein -
K4A87_RS16390 (K4A87_16300) 3420212..3421138 + 927 WP_208587617.1 Grx4 family monothiol glutaredoxin -
K4A87_RS16395 (K4A87_16305) 3421458..3422108 + 651 WP_208587619.1 DUF4433 domain-containing protein Toxin
K4A87_RS16400 (K4A87_16310) 3422147..3423178 + 1032 WP_238135557.1 macro domain-containing protein Antitoxin
K4A87_RS16405 (K4A87_16315) 3423285..3423845 - 561 WP_208587621.1 DUF924 family protein -
K4A87_RS16410 (K4A87_16320) 3423930..3424238 + 309 Protein_3046 amidohydrolase -
K4A87_RS16415 (K4A87_16325) 3424416..3425231 - 816 WP_208587622.1 cellulase -
K4A87_RS16420 (K4A87_16330) 3425497..3425737 + 241 Protein_3048 DegV family protein -
K4A87_RS16425 (K4A87_16335) 3425803..3426141 + 339 WP_208587623.1 hypothetical protein -
K4A87_RS16430 (K4A87_16340) 3426195..3427025 - 831 WP_208587624.1 S-formylglutathione hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(16-216)

Antitoxin

Macro domain

(5-117)


Sequences

Toxin        


Download         Length: 217 a.a.        Molecular weight: 24926.47 Da        Isoelectric Point: 8.4986

>T214269 WP_208587619.1 NZ_CP082178:3421458-3422108 [Xanthomonas fragariae]
MSRRYPNLNPDKALIWRIVHRDNLPWIMDNGLHCGNGGVQSPGWVSIGNPELIAKRANHPVPLAPGGFLNDYVPFYFTPF
SPMLRNIHTGWGGIQRRSNEEIVILVSSLHHVAARGWLFLFTDSHADYQLTTFHSDLANLCKIDWPLLQARDFRRDQEDP
AKFERYQAEALVHRHLPIDGLRGIVGYTDDMKLSIERQLKARNLTLPVHARPEWYF

Download         Length: 651 bp

>T214269 NZ_CP110017:c4635999-4635742 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin


Download         Length: 344 a.a.        Molecular weight: 38126.74 Da        Isoelectric Point: 5.3103

>AT214269 WP_238135557.1 NZ_CP082178:3422147-3423178 [Xanthomonas fragariae]
VEALVNTVNTVGVMGKGIALMFKERFNENFLRYAAACKAKQVRTGKVFVTEANELDGPRWIINFPTKQHWRGDSRIEWIT
EGLQDLRLFLIENKVGSIAIPPLGAGNGGLDWADVRPLIEESLAGLDTDIFVFEPTLKYQNVAKRSGVETLTPARALIAE
LVRRYWVLGVECSLLEIQKLAWFLERNIERAGLPTLDLRFAPNKYGPYADRLRHLLDGLDGSYLHCDKRIGDADPIDVIW
FDDARKSVVHAYLKSEAKQYAPALEATAALIDGFETPFGMELLATVDWLIAQGGVCPQVADMREGIRNWPGGADAAVRKD
RLFDDRALGIALERLTSSASAVT

Download         Length: 1032 bp

>AT214269 NZ_CP110017:c4635730-4635185 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References