Detailed information of TA system TA214267

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 1387930..1388609
• Replicon: chromosome
• Accession: NZ_CP082178
• Organism: Xanthomonas fragariae strain SHQP01

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: K4A87_RS06585
• Protein ID: WP_208590308.1
• Coordinates: 1388247..1388609 (-)
• Length: 121 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: K4A87_RS06580
• Protein ID: WP_208590306.1
• Coordinates: 1387930..1388247 (-)
• Length: 106 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K4A87_RS06560	1384199..1384489	-	291	WP_238135655.1	hypothetical protein	-
K4A87_RS06565 (K4A87_06510)	1384925..1385730	+	806	WP_208591587.1	IS5 family transposase	-
K4A87_RS06570 (K4A87_06515)	1385755..1386069	+	315	WP_238135656.1	hypothetical protein	-
K4A87_RS06575 (K4A87_06520)	1386397..1387884	+	1488	WP_208590304.1	site-specific integrase	-
K4A87_RS06580 (K4A87_06525)	1387930..1388247	-	318	WP_208590306.1	helix-turn-helix transcriptional regulator	Antitoxin
K4A87_RS06585 (K4A87_06530)	1388247..1388609	-	363	WP_208590308.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
K4A87_RS06595 (K4A87_06540)	1390432..1392597	+	2166	WP_208587611.1	type I secretion system permease/ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	1377444..1390179	12735

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (15-108)

Antitoxin

• HigA2-like, helix-turn-helix domain (12-91)

Sequences

Toxin

Protein

• Length: 121 a.a.
• Molecular weight: 13438.29 Da
• Isoelectric Point: 6.4748

>T214267 WP_208590308.1 NZ_CP082178:c1388609-1388247 [Xanthomonas fragariae]
MPEKPLIWVGSSRRDLAELPEDVKDTFGFALSEAQNGRTHVGAKLMAKGSLKGKGIYEVVDDYDGDTFRAVYTVEIEDAI
YALHCFQKKSKNGRETPKSDIDLIESRYQTALLDAKKVKI

Nucleotide

• Length: 363 bp

>T214267 NZ_CP110017:4453408-4453581 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Protein

• Length: 106 a.a.
• Molecular weight: 11121.71 Da
• Isoelectric Point: 4.8040

>AT214267 WP_208590306.1 NZ_CP082178:c1388247-1387930 [Xanthomonas fragariae]
MSIEIEVSSGNIYSDLGYSNAEEMKIKAALAGKISAFIADAHLTQAQAAAHMGISQAKVSEMLRGRFRGISEAKMMECLK
SFGQNVTISVTPAEVPDEAEISVAA

Nucleotide

• Length: 318 bp

>AT214267 NZ_CP110017:4453084-4453380 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGATT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG