Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1022742..1023520 Replicon chromosome
Accession NZ_CP082178
Organism Xanthomonas fragariae strain SHQP01

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag K4A87_RS04795 Protein ID WP_208589526.1
Coordinates 1022742..1023233 (-) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID G0CD67
Locus tag K4A87_RS04800 Protein ID WP_014508712.1
Coordinates 1023230..1023520 (-) Length 97 a.a.

Genomic Context

K4A87_RS04775K4A87_RS04780K4A87_RS04785K4A87_RS04790K4A87_RS04795K4A87_RS04800K4A87_RS04805K4A87_RS04810K4A87_RS04815K4A87_RS04820
Location: 1018526..1019431 (906 bp)
Type: Others
Protein ID: WP_208589518.1
Location: 1019654..1020097 (444 bp)
Type: Others
Protein ID: Protein_891
Location: 1020123..1020800 (678 bp)
Type: Others
Protein ID: WP_003490678.1
Location: 1021259..1022593 (1335 bp)
Type: Others
Protein ID: WP_208589524.1
Location: 1022742..1023233 (492 bp)
Type: Toxin
Protein ID: WP_208589526.1
Location: 1023230..1023520 (291 bp)
Type: Antitoxin
Protein ID: WP_014508712.1
Location: 1023596..1024001 (406 bp)
Type: Others
Protein ID: Protein_896
Location: 1024374..1024706 (333 bp)
Type: Others
Protein ID: WP_208589528.1
Location: 1025139..1026188 (1050 bp)
Type: Others
Protein ID: Protein_898
Location: 1026202..1026441 (240 bp)
Type: Others
Protein ID: WP_208589530.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
K4A87_RS04775 (K4A87_04735)1018526..1019431+906WP_208589518.130S ribosomal protein S6--L-glutamate ligase-
K4A87_RS047801019654..1020097+444Protein_891hypothetical protein-
K4A87_RS04785 (K4A87_04740)1020123..1020800+678WP_003490678.1response regulator transcription factor-
K4A87_RS04790 (K4A87_04745)1021259..1022593+1335WP_208589524.1HAMP domain-containing sensor histidine kinase-
K4A87_RS04795 (K4A87_04750)1022742..1023233-492WP_208589526.1GNAT family N-acetyltransferaseToxin
K4A87_RS04800 (K4A87_04755)1023230..1023520-291WP_014508712.1DUF1778 domain-containing proteinAntitoxin
K4A87_RS04805 (K4A87_04760)1023596..1024001-406Protein_896type I toxin-antitoxin system SymE family toxin-
K4A87_RS04810 (K4A87_04765)1024374..1024706-333WP_208589528.1hypothetical protein-
K4A87_RS04815 (K4A87_04770)1025139..1026188-1050Protein_898RHS repeat-associated core domain-containing protein-
K4A87_RS04820 (K4A87_04775)1026202..1026441-240WP_208589530.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(26-145)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17514.19 Da        Isoelectric Point: 8.9888

>T214266 WP_208589526.1 NZ_CP082178:c1023233-1022742 [Xanthomonas fragariae]
MTVSAPEPLTAHHRVEPFASGLESLDHWLKRRALKNQATGASRTVVACADDRVVAYYALASSAVAVDATPGRFRRNMPDP
IPVVVLGRLAVDQSLHGRGFGRALVQDAGKRILHAADTIGIRGLLVHALSADAKAFYERIGFEPSPLDPMVLVVTLEDLK
ASL

Download         Length: 492 bp

>T214266 NZ_CP110017:c3797200-3797093 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10648.20 Da        Isoelectric Point: 10.5480

>AT214266 WP_014508712.1 NZ_CP082178:c1023520-1023230 [Xanthomonas fragariae]
MSTPNTTPGKRETLNLRIKPEERSLIDRAAKARGKNRTDFMLDAARSAAEEALLDQTLIAASPDAYAAFLARLDMPPQPN
ARLRKTMQTPAPWEKA

Download         Length: 291 bp

>AT214266 NZ_CP110017:3797248-3797314 [Escherichia coli]
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A3E1LB51

References