214265

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 529524..529890 Replicon chromosome
Accession NZ_CP082178
Organism Xanthomonas fragariae strain SHQP01

Toxin (Protein)


Gene name EcnB Uniprot ID -
Locus tag K4A87_RS02460 Protein ID WP_208588796.1
Coordinates 529756..529890 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID -
Locus tag K4A87_RS02455 Protein ID WP_208588793.1
Coordinates 529524..529676 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K4A87_RS02440 (K4A87_02425) 525480..526496 - 1017 WP_238135624.1 hypothetical protein -
K4A87_RS02445 (K4A87_02430) 527614..528297 - 684 WP_208588787.1 dTMP kinase -
K4A87_RS02450 (K4A87_02435) 528492..529415 + 924 WP_208588790.1 arginase -
K4A87_RS02455 (K4A87_02440) 529524..529676 + 153 WP_208588793.1 entericidin A/B family lipoprotein Antitoxin
K4A87_RS02460 (K4A87_02445) 529756..529890 + 135 WP_208588796.1 entericidin A/B family lipoprotein Toxin
K4A87_RS02465 (K4A87_02450) 530215..531504 + 1290 WP_208588797.1 tryptophan--tRNA ligase -
K4A87_RS02470 (K4A87_02455) 531597..531761 + 165 WP_208591856.1 hypothetical protein -
K4A87_RS02480 (K4A87_02465) 532048..532641 + 594 Protein_460 drug/metabolite exporter YedA -
K4A87_RS02485 (K4A87_02470) 532659..533567 + 909 WP_208588801.1 EamA family transporter RarD -
K4A87_RS02490 (K4A87_02475) 533627..534742 - 1116 WP_208588802.1 alpha/beta fold hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.31 Da        Isoelectric Point: 10.2040

>T214265 WP_208588796.1 NZ_CP082178:529756-529890 [Xanthomonas fragariae]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T214265 NZ_CP110017:3374449-3374913 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAAACAGAAGAAACCCATTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5203.17 Da        Isoelectric Point: 9.4952

>AT214265 WP_208588793.1 NZ_CP082178:529524-529676 [Xanthomonas fragariae]
MKRLLTLMVLGLFSVGVMTGCNTVAGAGKDIQRAGSKVEKKADNCSDGKC

Download         Length: 153 bp

>AT214265 NZ_CP110017:3374114-3374449 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References