Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii(toxin)
Location 9136561..9137795 Replicon chromosome
Accession NZ_CP082164
Organism Bradyrhizobium sp. 186

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag IVB18_RS43485 Protein ID WP_247986220.1
Coordinates 9136875..9137795 (+) Length 307 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag IVB18_RS43480 Protein ID WP_247986219.1
Coordinates 9136561..9136875 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB18_RS43470 (IVB18_42895) 9132113..9136171 - 4059 WP_256477132.1 helix-turn-helix transcriptional regulator -
IVB18_RS43475 9136174..9136527 - 354 WP_247986218.1 hypothetical protein -
IVB18_RS43480 9136561..9136875 + 315 WP_247986219.1 hypothetical protein Antitoxin
IVB18_RS43485 (IVB18_42905) 9136875..9137795 + 921 WP_247986220.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IVB18_RS43490 (IVB18_42915) 9138674..9140134 - 1461 WP_247986221.1 HEPN domain-containing protein -
IVB18_RS43495 (IVB18_42920) 9140178..9140471 + 294 WP_247986222.1 hypothetical protein -
IVB18_RS43505 (IVB18_42930) 9141002..9141436 - 435 WP_247986223.1 phasin -
IVB18_RS43510 (IVB18_42935) 9141716..9142162 - 447 WP_247986224.1 phasin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-272)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 307 a.a.        Molecular weight: 34235.63 Da        Isoelectric Point: 5.6592

>T214262 WP_247986220.1 NZ_CP082164:9136875-9137795 [Bradyrhizobium sp. 186]
MAKVLKNLAASIRDRLLQHTKQHGDVYQRILTRYAIERLLFRLSLTEAAEHYVLKGAMLFVTWPEHVFRPTGDLDLLGHG
DPEPAAIVELFTRICQVEAPDDGIIFDPATLTVEPVREGDKYQGVHLNLKGELARAVIPVQVDIGFGDHVYPPPERRMFP
CLLPNLPAANILMYPPETVIAEKFEVMIRFGTANGRIKDFYDIWVTLRTFGFELPELVEAVGGTLRRRETAVPTEIPVGL
TEAFATIAADRGLWTGFLRRNLPTIQPPSFPELQLELQRFLGPVITGLAVPEGAKGRWDPDGGAWV

Download         Length: 921 bp

>T214262 NZ_CP110017:c3134059-3133652 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11680.56 Da        Isoelectric Point: 9.5973

>AT214262 WP_247986219.1 NZ_CP082164:9136561-9136875 [Bradyrhizobium sp. 186]
MTIPHKARTPNAQVMRLEIVRATGDVLTAGVEHVRVEGVDVPIYGVAKTIADCFKHRRHVGEDVAIEALRDALRQRKTTE
SELMKYAGIDRVTARIEPYIKAMQ

Download         Length: 315 bp

>AT214262 NZ_CP110017:c3134306-3134040 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References