Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 7872801..7873504 Replicon chromosome
Accession NZ_CP082164
Organism Bradyrhizobium sp. 186

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVB18_RS37970 Protein ID WP_247985367.1
Coordinates 7873079..7873504 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVB18_RS37965 Protein ID WP_247985366.1
Coordinates 7872801..7873082 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB18_RS37945 (IVB18_37455) 7867932..7868834 - 903 WP_247985362.1 sugar ABC transporter permease -
IVB18_RS37950 (IVB18_37460) 7868834..7869919 - 1086 WP_247985363.1 ABC transporter ATP-binding protein -
IVB18_RS37955 (IVB18_37465) 7869931..7871022 - 1092 WP_247985364.1 ABC transporter ATP-binding protein -
IVB18_RS37960 (IVB18_37470) 7871019..7872569 - 1551 WP_247985365.1 glycerol-3-phosphate dehydrogenase -
IVB18_RS37965 (IVB18_37475) 7872801..7873082 + 282 WP_247985366.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IVB18_RS37970 (IVB18_37480) 7873079..7873504 + 426 WP_247985367.1 type II toxin-antitoxin system VapC family toxin Toxin
IVB18_RS37975 (IVB18_37485) 7873610..7874458 - 849 WP_247985368.1 DeoR/GlpR family DNA-binding transcription regulator -
IVB18_RS37980 (IVB18_37490) 7874549..7875235 - 687 WP_247985369.1 HAD-IA family hydrolase -
IVB18_RS37985 (IVB18_37495) 7875186..7875854 + 669 WP_247991824.1 nuclear transport factor 2 family protein -
IVB18_RS37990 (IVB18_37500) 7876092..7876286 - 195 WP_247985370.1 hypothetical protein -
IVB18_RS37995 (IVB18_37505) 7876478..7876888 - 411 WP_247985371.1 acyl-CoA thioesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(14-77)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15416.68 Da        Isoelectric Point: 5.7220

>T214260 WP_247985367.1 NZ_CP082164:7873079-7873504 [Bradyrhizobium sp. 186]
VNLLLDTNVLSEVQRPAPDSKVLAWLDTVDEDRAFISVASIAELRRGIALMEDGRRRTALAAWLAHNLPTRFAGRILPID
HAVAERWGDLMAQSRRSGVALSVMDGFFAATALANNLTLVTRNVKDLAAFGVPLLNPWDDA

Download         Length: 426 bp

>T214260 NZ_CP110017:2868583-2868912 [Escherichia coli]
ATGAACACTCTACCTGCTACAATTTCGCAGGCGGCGAAGCCCTGCCTGTCGCCAGTGGCTGTCTGGCAAATGCTACTGAC
ACGCCTGCTGGAACAACACTATGGCCTGACACTGAACGACACGCCGTTCAGTGATGAAACTGTTATTAAGGAACATATCG
ATGCTGGTATCACTCTGGCCGATGCAGTCAATTTTCTGGTGGAAAAGTACGAACTGGTACGTATCGATCACAGAGGATTT
TCGTGGCAACAACAGTCTCCATATATTTCCGTAGTAGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACTAA
TGTGAAATAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10167.47 Da        Isoelectric Point: 7.3215

>AT214260 WP_247985366.1 NZ_CP082164:7872801-7873082 [Bradyrhizobium sp. 186]
MTEHSTAPRSPATDSWTLANAKARLSEVIDRAQAGPQIITRHGKPNAVVVSAEEWARKTARKGTLAEFLLASPLRGADLE
LERVHDAPRDEMP

Download         Length: 282 bp

>AT214260 NZ_CP110017:2868245-2868562 [Escherichia coli]
ATGAGCAACACCACATGGGGCCTGCAGCGAGATATCACGCCGCGCCTGGGAGCACGTCTGGTGCAGGAGGGCAACCAGCT
GCACTATCTGGCTGACCGGGCCAGTATCACCGGTAAGTTTAGTGACGCCGAATGTCCTAAGCTGGATGTGGTATTTCCAC
ATTTTATCAGCCAGATAGAGTCGATGCTGACCACTGGTGAACTGAATCCCCGCCATGCCCAATGCGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACTCTTGGTAGTTGCGGCTACGTATACATCGCTGTTTACCCCACTCAACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References