Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 7128977..7129617 Replicon chromosome
Accession NZ_CP082164
Organism Bradyrhizobium sp. 186

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag IVB18_RS34530 Protein ID WP_247984767.1
Coordinates 7128977..7129267 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IVB18_RS34535 Protein ID WP_247984768.1
Coordinates 7129267..7129617 (+) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB18_RS34515 (IVB18_34045) 7124551..7125330 + 780 WP_247984765.1 enoyl-CoA hydratase -
IVB18_RS34520 (IVB18_34050) 7125335..7127209 - 1875 WP_247991799.1 acetyl-CoA hydrolase/transferase C-terminal domain-containing protein -
IVB18_RS34525 (IVB18_34055) 7127476..7128873 + 1398 WP_247984766.1 TolC family outer membrane protein -
IVB18_RS34530 (IVB18_34060) 7128977..7129267 + 291 WP_247984767.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IVB18_RS34535 (IVB18_34065) 7129267..7129617 + 351 WP_247984768.1 putative addiction module antidote protein Antitoxin
IVB18_RS34540 (IVB18_34070) 7129745..7130713 + 969 WP_247984769.1 alpha/beta hydrolase -
IVB18_RS34545 (IVB18_34075) 7130748..7131167 + 420 WP_247984770.1 hypothetical protein -
IVB18_RS34550 (IVB18_34080) 7131160..7132260 + 1101 WP_247984771.1 hypothetical protein -
IVB18_RS34555 (IVB18_34085) 7132238..7132576 + 339 WP_247984772.1 hypothetical protein -
IVB18_RS34560 (IVB18_34090) 7132587..7134185 - 1599 WP_247984773.1 FAD-binding oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(13-107)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11053.69 Da        Isoelectric Point: 10.6580

>T214259 WP_247984767.1 NZ_CP082164:7128977-7129267 [Bradyrhizobium sp. 186]
MIEVRQTEHFSEWLNRLKDANAAARITVRIRRMAMGNAGDSKSVGRNVREMRVDYGPGYRIYYVRRGARIVILLCGGDKR
TQQQDIEQAQKLAETV

Download         Length: 291 bp

>T214259 NZ_CP110017:2857048-2858121 [Escherichia coli]
ATGACAATCAGGAGTTACAAAAACTTAAATCTGGTCAGGGCAAATATCGAGACTGAATCCAGACAATTCATTGAAAATAA
AAACTATTCAATCCAATCAATTGGTCCTATGCCAGGGTCAAGGGCTGGGCTTCGGGTCGTATTTACCAGACCAGGGGTTA
ACTTGGCAACTGTGGACATTTTTTATAACGGGGACGGTTCGACTACAATTCAATATCTCACTGGAGCCAATCGTTCTCTG
GGCCAAGAGTTAGCGGATCATCTTTTTGAAACCATCAATCCTGCTGAATTTGAGCAGGTAAATATGGTACTGCAAGGATT
TGTAGAGACAAGCGTTCTACCTGTACTTGAGCTATCAGCAGATGAATCGCATATAGAGTTCAGAGAACACTCTCGTAACG
CTCATACCGTAGTGTGGAAAATTATTTCCACCAGCTATCAGGACGAATTGACTGTGAGCCTGCATATCACAACAGGTAAG
CTCCAGATTCAGGGCCGACCGCTGTCATGTTACAGAGTTTTCACGTTTAACTTGGCAGCCCTGCTTGATTTACAGGGTTT
GGAGAAAGTGCTAATCCGCCAGGAGGATGGTAAAGCTAATATTGTTCAACAGGAGGTTGCCCGCACTTACTTGCAGACTG
TAATGGCCGATGCTTACCCGCATCTCCACGTGACTGCCGAAAAATTGCTCGTTTCAGGGCTATGTGTTAAACTCGCCGCC
CCTGATTTGCCTGACTACTGTATGTTACTTTATCCTGAACTACGCACCATTGAAGGTGTCTTAAAAAGTAAGATGAGTGG
GTTAGGCATGCCAGTACAGCAGCCGGCAGGTTTTGGAACTTACTTTGATAAACCTGCTGCTCATTACATTCTGAAACCGC
AATTTGCAGCTACTCTTAGACCGGAACAGATTAACATCATCAGCACAGCCTATACTTTTTTTAATGTGGAACGTCATTCT
CTGTTCCACATGGAAACTGTGGTCGATGCCAGCCGTATGATTTCTGATATGGCCCGGTTGATGGGTAAAGCCACTAGAGC
GTGGGGAATAATCAAGGACTTATATATTGTTTGA

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 12244.00 Da        Isoelectric Point: 10.9396

>AT214259 WP_247984768.1 NZ_CP082164:7129267-7129617 [Bradyrhizobium sp. 186]
MPRVAKTAAKTVSKTTRFDAADYLNTEERQAAYIAAALETGDADFVRDALGLVARARGMSGIAKKAGLNRESLYKALGET
GNPEFGTVMRIVGALGLTLSAQPAASGRTSKRRRVA

Download         Length: 351 bp

>AT214259 NZ_CP110017:2858114-2858485 [Escherichia coli]
TTGTTTGAAATCACCGGAATTAACGTCTCAGGGGCTCTAAAAGCTGTCGTTATGGCGACCGGCTTCGAGAACCCTTTGTC
CTCAGTTAATGAAATTGAGACGAAACTTTCTGCCCTACTGGGTAGTGAGACCACTGGTGAAATCCTTTTTGACCTCTTGT
GCGCTAACGGTCCAGAGTGGAACCGCTTCGTTACGCTGGAAATGAAATATGGCCGGATCATGCTGGATACGGCCAAAATT
ATTGATGAGCAGGACGTTCCGACACATATCCTGAGCAAACTGACTTTTACTTTACGTAATCATCCTGAGTACCTAGAAGC
CTCTGTTTTGTCTCCCGATGATGTACGCCAAGTCCTGTCAATGGATTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References