Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 6042048..6042586 Replicon chromosome
Accession NZ_CP082164
Organism Bradyrhizobium sp. 186

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag IVB18_RS29090 Protein ID WP_247983826.1
Coordinates 6042048..6042314 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IVB18_RS29095 Protein ID WP_247983827.1
Coordinates 6042320..6042586 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB18_RS29075 (IVB18_28680) 6039298..6039729 + 432 WP_247983823.1 DUF983 domain-containing protein -
IVB18_RS29080 (IVB18_28685) 6039762..6040523 + 762 WP_247983824.1 NUDIX hydrolase -
IVB18_RS29085 (IVB18_28690) 6040682..6042007 + 1326 WP_247983825.1 LLM class flavin-dependent oxidoreductase -
IVB18_RS29090 (IVB18_28695) 6042048..6042314 - 267 WP_247983826.1 Txe/YoeB family addiction module toxin Toxin
IVB18_RS29095 (IVB18_28700) 6042320..6042586 - 267 WP_247983827.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IVB18_RS29100 (IVB18_28705) 6042823..6042990 + 168 WP_045008041.1 50S ribosomal protein L33 -
IVB18_RS29105 (IVB18_28710) 6043377..6044750 - 1374 WP_247983828.1 group II intron reverse transcriptase/maturase -
IVB18_RS29110 (IVB18_28715) 6045271..6045654 + 384 Protein_5816 transposase -
IVB18_RS29115 (IVB18_28720) 6046062..6046508 - 447 WP_247983829.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10618.19 Da        Isoelectric Point: 9.4826

>T214258 WP_247983826.1 NZ_CP082164:c6042314-6042048 [Bradyrhizobium sp. 186]
MLIAWTEIAWQDYLQRQKEDEKILTAINDLIKDIKRDPFRGIGKPEPLKHDLRGWWSRRVTGEHRLVYRLQGKDDGQQLV
IAQCRYHY

Download         Length: 267 bp

>T214258 NZ_CP110017:c2178732-2178481 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9758.00 Da        Isoelectric Point: 4.5037

>AT214258 WP_247983827.1 NZ_CP082164:c6042586-6042320 [Bradyrhizobium sp. 186]
MANVSYTELRSNLAAYMDQVCDDRAPLVVTRQNARSVVMLSEEEYEGLVETVHLLKSPANAARLLRSIKEADEGRLVEHE
LIEPGSTG

Download         Length: 267 bp

>AT214258 NZ_CP110017:c2178484-2178230 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References