Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 5429204..5429844 Replicon chromosome
Accession NZ_CP082164
Organism Bradyrhizobium sp. 186

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVB18_RS26030 Protein ID WP_247983283.1
Coordinates 5429204..5429599 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVB18_RS26035 Protein ID WP_247983284.1
Coordinates 5429599..5429844 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB18_RS26010 (IVB18_25630) 5424858..5426039 + 1182 WP_247983279.1 patatin-like phospholipase family protein -
IVB18_RS26015 (IVB18_25635) 5426174..5426941 + 768 WP_247983280.1 TetR/AcrR family transcriptional regulator -
IVB18_RS26020 (IVB18_25640) 5427205..5427810 + 606 WP_247983281.1 PepSY domain-containing protein -
IVB18_RS26025 (IVB18_25645) 5428086..5429123 + 1038 WP_247983282.1 aspartate-semialdehyde dehydrogenase -
IVB18_RS26030 (IVB18_25650) 5429204..5429599 - 396 WP_247983283.1 type II toxin-antitoxin system VapC family toxin Toxin
IVB18_RS26035 (IVB18_25655) 5429599..5429844 - 246 WP_247983284.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
IVB18_RS26040 (IVB18_25660) 5429935..5431005 - 1071 WP_247983285.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
IVB18_RS26045 (IVB18_25665) 5431136..5431600 - 465 WP_247983286.1 peptidylprolyl isomerase -
IVB18_RS26050 (IVB18_25670) 5431597..5432007 - 411 WP_247983287.1 hypothetical protein -
IVB18_RS26055 (IVB18_25675) 5432016..5432591 - 576 WP_247983288.1 peptidylprolyl isomerase -
IVB18_RS26060 (IVB18_25680) 5432629..5433126 - 498 WP_247983289.1 pantetheine-phosphate adenylyltransferase -
IVB18_RS26065 (IVB18_25685) 5433383..5433640 + 258 WP_247983290.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-125)

Antitoxin

Antitoxin VapB-like

(2-80)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14169.35 Da        Isoelectric Point: 4.8361

>T214257 WP_247983283.1 NZ_CP082164:c5429599-5429204 [Bradyrhizobium sp. 186]
MVLDTSAIIAAITNEPDGPRYRAAMRDADNLLISAVAVLETRIVLFARLGPQAVELFDELLRSTTLVVVPFDDEMSKGAF
EAFRQYGKGSGHPAQLNIVDCAVYALAKSRSQPLLFKGGDFGRTDIAIALI

Download         Length: 396 bp

>T214257 NZ_CP110017:c2178484-2178230 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9336.55 Da        Isoelectric Point: 4.8779

>AT214257 WP_247983284.1 NZ_CP082164:c5429844-5429599 [Bradyrhizobium sp. 186]
MNIRSTKVDQLAQRLSRLTGEDIETALERAIEERLSRLEPSVARDRKATLDSFFERALLLRVLDARSSDEIVEYDRFGLP
S

Download         Length: 246 bp

>AT214257 NZ_CP110017:c2178732-2178481 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References