Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 6564602..6565308 Replicon chromosome
Accession NZ_CP082161
Organism Bradyrhizobium sp. 195

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IVB26_RS30710 Protein ID WP_247968788.1
Coordinates 6564883..6565308 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IVB26_RS30705 Protein ID WP_247968787.1
Coordinates 6564602..6564886 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVB26_RS30685 (IVB26_30475) 6559673..6560647 - 975 WP_247968783.1 sugar ABC transporter permease -
IVB26_RS30690 (IVB26_30480) 6560647..6561732 - 1086 WP_247968784.1 ABC transporter ATP-binding protein -
IVB26_RS30695 (IVB26_30485) 6561745..6562821 - 1077 WP_247968785.1 ABC transporter ATP-binding protein -
IVB26_RS30700 (IVB26_30490) 6562818..6564368 - 1551 WP_247968786.1 glycerol-3-phosphate dehydrogenase -
IVB26_RS30705 (IVB26_30495) 6564602..6564886 + 285 WP_247968787.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IVB26_RS30710 (IVB26_30500) 6564883..6565308 + 426 WP_247968788.1 type II toxin-antitoxin system VapC family toxin Toxin
IVB26_RS30715 (IVB26_30505) 6565312..6566157 - 846 WP_128916585.1 DeoR/GlpR family DNA-binding transcription regulator -
IVB26_RS30720 (IVB26_30510) 6566248..6566934 - 687 WP_247968789.1 HAD-IA family hydrolase -
IVB26_RS30725 (IVB26_30515) 6567089..6567541 + 453 WP_247319618.1 nuclear transport factor 2 family protein -
IVB26_RS30730 (IVB26_30520) 6567809..6568000 - 192 WP_246929190.1 hypothetical protein -
IVB26_RS30735 (IVB26_30525) 6568237..6568647 - 411 WP_247968790.1 acyl-CoA thioesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(15-78)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15509.84 Da        Isoelectric Point: 6.2316

>T214253 WP_247968788.1 NZ_CP082161:6564883-6565308 [Bradyrhizobium sp. 195]
VNLLLDTNVLSEIRRPAPSPKVLAWLDTIDEDRAFISVASIAELRRGVALLEDGRRRTALAAWLAHDLPARFAERVLPIN
HAVAERWGDLMAQSRRSGVALSVMDGFFAATALTHGLTLVTRNVKDFAAFGVPLLDPWDDV

Download         Length: 426 bp

>T214253 NZ_CP110017:c1679816-1678494 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10242.54 Da        Isoelectric Point: 5.7118

>AT214253 WP_247968787.1 NZ_CP082161:6564602-6564886 [Bradyrhizobium sp. 195]
MADRNTAPDTLPADDTWTLANAKARLSEVIDRAQAGPQVITRHGKPSAVVVSAEEWARKTARKGTLAEFLLASPLRGADL
ELERVHDAPRDEMP

Download         Length: 285 bp

>AT214253 NZ_CP110017:c1680082-1679816 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References