Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 1718..2286 Replicon plasmid pRop44186_b
Accession NZ_CP082158
Organism Rhodococcus opacus strain DSM 44186

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FXW36_RS00015 Protein ID WP_095870972.1
Coordinates 1718..1966 (-) Length 83 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FXW36_RS00020 Protein ID WP_133983709.1
Coordinates 1996..2286 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FXW36_RS40705 596..724 + 129 Protein_0 Clp protease N-terminal domain-containing protein -
FXW36_RS40710 748..947 + 200 Protein_1 hypothetical protein -
FXW36_RS40715 1147..1269 - 123 Protein_2 phosphate transport system regulatory protein PhoU -
FXW36_RS00015 (FXW36_00015) 1718..1966 - 249 WP_095870972.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FXW36_RS00020 (FXW36_00020) 1996..2286 - 291 WP_133983709.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FXW36_RS00025 (FXW36_00025) 2634..2972 - 339 WP_133983711.1 hypothetical protein -
FXW36_RS00030 (FXW36_00030) 3240..3476 - 237 WP_133983713.1 CopG family transcriptional regulator -
FXW36_RS00035 (FXW36_00035) 3466..3730 - 265 Protein_7 BrnT family toxin -
FXW36_RS00040 (FXW36_00040) 4025..4681 + 657 WP_259465533.1 hypothetical protein -
FXW36_RS00045 (FXW36_00045) 5174..5710 + 537 WP_120659062.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..52207 52207


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(29-80)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-69)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9057.35 Da        Isoelectric Point: 10.1359

>T214250 WP_095870972.1 NZ_CP082158:c1966-1718 [Rhodococcus opacus]
MARSAARALATSLPEKVATAVYEFVTGPLLENPRRVGKPLDPPLAPAYSARRGTYRVLYLINDENRTVEVTAISHRADAY
RT

Download         Length: 249 bp

>T214250 NZ_CP110017:c1309804-1309697 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10475.60 Da        Isoelectric Point: 4.3744

>AT214250 WP_133983709.1 NZ_CP082158:c2286-1996 [Rhodococcus opacus]
MYMTTLPVADARAQLSRLVDEAEHTHERFEITRNGHRAAVLLGADDYDALRETIAVLSDTDLLAAHLAGRAEVEGGDVVD
ADELARLMRDARSSGE

Download         Length: 291 bp

>AT214250 NZ_CP110017:1309851-1309917 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References