Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 5178138..5178282 | Replicon | chromosome |
| Accession | NZ_CP082154 | ||
| Organism | Klebsiella pneumoniae strain Kp11-81 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 5178144..5178246 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 5178138..5178282 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6977_RS25455 (K6977_25405) | 5173911..5174192 | + | 282 | WP_032419786.1 | hypothetical protein | - |
| K6977_RS25460 (K6977_25410) | 5174202..5174630 | + | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| K6977_RS25465 (K6977_25415) | 5174880..5176385 | - | 1506 | WP_020956680.1 | hypothetical protein | - |
| K6977_RS25470 | 5176524..5176719 | - | 196 | Protein_4979 | DNA polymerase V | - |
| K6977_RS25475 (K6977_25420) | 5177174..5177653 | - | 480 | WP_032419797.1 | lysis protein | - |
| K6977_RS25480 (K6977_25425) | 5177730..5178011 | + | 282 | Protein_4981 | tyrosine-type recombinase/integrase | - |
| - | 5178138..5178282 | + | 145 | - | - | Antitoxin |
| - | 5178144..5178246 | - | 103 | - | - | Toxin |
| K6977_RS25485 (K6977_25430) | 5178405..5178743 | - | 339 | WP_002911404.1 | YebY family protein | - |
| K6977_RS25490 (K6977_25435) | 5178760..5179629 | - | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| K6977_RS25495 (K6977_25440) | 5179633..5180007 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| K6977_RS25500 (K6977_25445) | 5180120..5180350 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| K6977_RS25505 (K6977_25450) | 5180429..5181088 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| K6977_RS25510 (K6977_25455) | 5181092..5183152 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T214240 NZ_CP082154:c5178246-5178144 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT214240 NZ_CP082154:5178138-5178282 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
