Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2052976..2053247 Replicon chromosome
Accession NZ_CP082120
Organism Escherichia coli strain PC-NDM34

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2053106..2053209 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2052976..2053247 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K5P75_RS09890 2049531..2050193 - 663 WP_000944256.1 exodeoxyribonuclease X -
K5P75_RS09895 2050217..2050873 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
K5P75_RS09900 2050975..2051205 - 231 WP_000916763.1 DNA polymerase III subunit theta -
K5P75_RS09905 2051344..2051718 + 375 WP_000204699.1 CopC domain-containing protein YobA -
K5P75_RS09910 2051722..2052594 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
K5P75_RS09915 2052607..2052948 + 342 WP_000976492.1 YebY family protein -
- 2052976..2053247 - 272 - - Antitoxin
- 2053106..2053209 + 104 - - Toxin
K5P75_RS09920 2053344..2054000 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
K5P75_RS09925 2054001..2054192 - 192 WP_000457842.1 YebW family protein -
K5P75_RS09930 2054297..2054533 - 237 WP_001295499.1 YebV family protein -
K5P75_RS09935 2054651..2056090 - 1440 WP_024198516.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T214119 NZ_CP082120:2053106-2053209 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT214119 NZ_CP082120:c2053247-2052976 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References