Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2022762..2022907 | Replicon | chromosome |
| Accession | NZ_CP082037 | ||
| Organism | Klebsiella pneumoniae strain KP18-2172 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2022798..2022900 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2022762..2022907 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6161_RS09965 | 2017892..2019952 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| K6161_RS09970 | 2019956..2020615 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| K6161_RS09975 | 2020694..2020924 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| K6161_RS09980 | 2021037..2021411 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| K6161_RS09985 | 2021415..2022284 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| K6161_RS09990 | 2022301..2022639 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2022762..2022907 | - | 146 | - | - | Antitoxin |
| - | 2022798..2022900 | + | 103 | - | - | Toxin |
| K6161_RS09995 | 2023275..2023418 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| K6161_RS10000 | 2023523..2024491 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| K6161_RS10005 | 2024648..2025301 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| K6161_RS10010 | 2025298..2025489 | - | 192 | WP_002911395.1 | YebW family protein | - |
| K6161_RS10015 | 2025587..2025826 | - | 240 | WP_002911393.1 | YebV family protein | - |
| K6161_RS10020 | 2025942..2027375 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T214062 NZ_CP082037:2022798-2022900 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT214062 NZ_CP082037:c2022907-2022762 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
